比较基层医院耻骨上经膀胱前列腺切除术（TVP）和等离子经尿道前列腺电切术（PKRP）治疗大体积前列腺患者的安全性及疗效。

将2009年6月至2012年5月在佛山市禅城区中心医院泌尿外科经尿动力学与超声检查诊断膀胱出口梗阻并前列腺体积>80 ml的80例患者将随机分为TVP和PKRP组，记录并比较所有患者术前、术后3个月、12个月随访资料，包括国际前列腺症状评分（IPSS）、生活质量评分（QOL）、最大尿流率（Qmax）、围手术期资料、术中情况、术后并发症情况等。

80例入组患者中，69例完成12个月的随访，两组患者在手术时间、手术前列腺切除重量差异无统计学意义，PKRP组出血量、留置尿管时间、膀胱冲洗时间、住院天数均显著优于TVP组，术后随访3个月、12个月，两组患者IPSS、Qmax、QOL差异无统计学意义。

TVP和PKRP都可用于治疗前列腺体积80 ml以上前列腺增生患者，但PKRP创伤更小、恢复更快，利于在基层医院临床推广。

To compare the safety and efficacy of transvesical prostatectomy(TVP)and plasma kinetic resection of prostate (PKRP) for treating big volume prostate in primary hospital.

Eighty patients with urodynamic obstruction and whose prostate volume was bigger than 80 ml were prospectively randomized and assigned to TVP group or PKRP group. Patients were assessed preoperatively and followed up at 3 and 12 months postoperatively. International prostate symptom score, quality of life score and maximum flow rate were obtained. Perioperative data and postoperative complications were also recorded.

Among 80 participants, 69 patients completed 12 months of follow-up. There were no significant differences in operation time and the weight of resecting prostate between the two groups. The PKRP group had significantly less blood loss of operation, shorter postoperative bladder washing time, shorter postoperative catheterization time and shorter hospital stay than the TVP group. There were no significant differences in International prostate symptom score, quality of life score and maximum flow rate between the two groups at 3 or 12 months of follow-up.

Both PKRP and TVP are effective alternatives for treatment of benign prostatic hyperplasia whose volume, is bigger than 80 ml, but PKRP is less wound and recover rapidly so that it worth to popularize in primary hospital.