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中华腔镜泌尿外科杂志(电子版) ›› 2020, Vol. 14 ›› Issue (03) : 181 -184. doi: 10.3877/cma.j.issn.1674-3253.2020.03.005

所属专题： 文献；

临床研究

超声造影鉴别膀胱良恶性占位的诊断价值初探
郑剑1,†(), 张敏1, 王青娟1, 黄晶1, 陈远森1, 彭翔1, 邹思源1, 黄启平1, 郑荣琴2   
  1. 1. 518115　深圳市龙岗区第三人民医院超声科
    2. 510630　广州，中山大学附属第三医院超声科
  • 收稿日期:2020-01-15 出版日期:2020-06-01
  • 通信作者: 郑剑
  • 基金资助:
    广东省基础与应用基础研究基金项目(2019A1515011403)

The value of contrast enhanced ultrasound in differentiating benign and malignant bladder neoplasms

Jian Zheng1,†(), Min Zhang1, Qingjuan Wang1, Jing Huang1, Yuansen Chen1, Xiang Peng1, Siyuan Zou1, Qiping Huang1, Rongqin Zheng2   

  1. 1. Department of Ultrasound, the Third Hospital of Longgang, Shenzhen 518115, China
    2. Department of Ultrasound, the Third Affiliated Hospital of Sun Yat-Sen University, Guangzhou 510630, China
  • Received:2020-01-15 Published:2020-06-01
  • Corresponding author: Jian Zheng
  • About author:
    Corresponding author: Zheng Jian, Email:
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郑剑, 张敏, 王青娟, 黄晶, 陈远森, 彭翔, 邹思源, 黄启平, 郑荣琴. 超声造影鉴别膀胱良恶性占位的诊断价值初探[J]. 中华腔镜泌尿外科杂志(电子版), 2020, 14(03): 181-184.

Jian Zheng, Min Zhang, Qingjuan Wang, Jing Huang, Yuansen Chen, Xiang Peng, Siyuan Zou, Qiping Huang, Rongqin Zheng. The value of contrast enhanced ultrasound in differentiating benign and malignant bladder neoplasms[J]. Chinese Journal of Endourology(Electronic Edition), 2020, 14(03): 181-184.

目的

探讨超声造影鉴别膀胱良恶性占位的诊断价值。

方法

对2018年5月至2019年12月在深圳市龙岗区第三人民医院因膀胱占位行超声造影检查的15例患者共17个病灶进行分析，观察病变位置、大小、数目，肿块内是否有血流信号，超声造影是否有增强及造影剂到达时间，增强模式。

结果

17个病灶中恶性病灶13个（膀胱乳头状尿路上皮癌12个、膀胱肉瘤样癌1个），良性病灶4个（腺性膀胱炎1个，膀胱沉积物或凝血块3个），病灶大小（2.8±1.5）cm。超声造影诊断恶性病灶准确率高于常规超声（χ2=0.215，P=0.046）。膀胱乳头状尿路上皮癌超声造影到达时间为（20.7±6.0）秒，增强模式为均匀高增强、缓慢慢退；膀胱肉瘤样癌超声造影到达时间为13秒，增强模式为均匀高增强、快速消退；腺性膀胱炎超声造影到达时间为24秒；3个膀胱凝血块表现为无增强。

结论

超声造影能明显提高常规超声对膀胱占位的检出和鉴别诊断能力。

关键词: 超声, 超声造影, 膀胱占位
Objective

To evaluate the value of contrast enhanced ultrasound in differentiating benign and malignant bladder neoplasms.

Methods

From May 2018 to December 2019, 17 lesions of 15 patients with bladder neoplasms, underwent contrast enhanced ultrasound (CEUS) in the Third Hospital of Longgang were included. The location, size, number, color doppler, arrival time and enhanced mode of CEUS were observed.

Results

Among the 17 lesions, 13 were malignant (12 bladder papillary urothelial carcinoma, 1 bladder sarcomatoid carcinoma), 4 were benign (1 cystitis glandular, 3 bladder deposits or clots), and the mean size was (2.8±1.5) cm. The accuracy of CEUS was higher than conventional ultrasound in diagnosing bladder malignant neoplasms (χ2=0.215, P=0.046). The arrival time of CEUS was (20.7±6.0) s in bladder papillary urothelial carcinoma with fast wash-in and slow wash-out. That was 13 s in bladder sarcomatoid carcinoma with fast wash-in and fast wash-out. That was 24 s in cystitis glandular. The bladder deposits or clots showed no wash-in.

Conclusion

Contrast enhanced ultrasonography improve the ability of conventional ultrasound in detecting and differentiating urinary bladder neoplasms.

Key words: Ultrasonography, Contrast enhanced ultrasound, Bladder neoplasms
图1~3 常规超声和超声造影对膀胱良恶性占位的基本表现
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