肾窦Castleman病一例报告

doi:10.3877/cma.j.issn.1674-3253.2025.04.021

中华腔镜泌尿外科杂志(电子版) ›› 2025, Vol. 19 ›› Issue (04) : 528 -531. doi: 10.3877/cma.j.issn.1674-3253.2025.04.021

所属专题：经典病例；

病例报告

肾窦Castleman病一例报告

常颜, 张剑飞^†(

)

050000　石家庄，中国人民解放军联勤保障部队第九八〇医院泌尿外科

收稿日期:2023-10-16 出版日期:2025-08-01
通信作者: 张剑飞

A case report of Castleman Disease in the renal sinus

Yan Chang, Jianfei Zhang^†()

Department of Urology, 980th Hospital of the Joint Logistics Support Force of the People's Liberation Army, Shijiazhuang 050000, China

Received:2023-10-16 Published:2025-08-01
Corresponding author: Jianfei Zhang

全文 ( ) 下载PDF ( ) 导出引用

本文报告一例肾窦内Castleman病男性病例，以无痛肉眼全程血尿为主要临床表现，CTU显示右肾盂内类圆形肿物，增强呈明显强化，初步诊断为肾盂肿瘤。在全麻下行后腹腔镜肾输尿管全长切除术，术后病理证实为肾窦castleman病。

关键词: Castleman病, 肾窦

This paper reports a male case of Castleman's disease in renal sinus, with painless gross hematuria as the main clinical manifestation. CTU showed a round-shaped tumor in the right renal pelvis, which was obviously enhanced. The initial diagnosis was renal pelvis tumor. The patient underwent a total nephroureterectomy via laparoscopic retroperitoneal approach under general anesthesia, and postoperative pathology confirmed Castleman disease in the renal sinus.

Key words: Castleman Disease, Renal sinus

图1 肾窦Castleman病CT检查注：箭头示病灶；a为平扫，b为增强，c为增强排泄期

图3 肾窦Castleman病术后病理

[1]	Castleman B, Iverson L, Menendez VP. Localized mediastinal lymphnode hyperplasia resembling thymoma[J]. Cancer, 1956, 9(4): 822-830. DOI: 10.1002/1097-0142(195607/08)9:4<822::aid-cncr2820090430>3.0.co;2-4.
[2]	李理, 张蕊, 王天有. Castleman病的发病机制及治疗研究进展[J]. 中国小儿血液与肿瘤杂志, 2022, 27(5): 336-339, 348. DOI: 10.3969/j.issn.1673-5323.2022.05.010.
[3]	Gupta A, Ayyar B, Zia H, et al. Hyaline-vascular type Castleman's disease, sarcoidosis, and crohns disease[J]. Indian J Hematol Blood Transfus, 2016, 32(Suppl 1): 335-339. DOI: 10.1007/s12288-015-0580-8.
[4]	Raboso E, Barberá R, Guimaraens L, et al. Castleman's disease as an unusual cause for dysphagia and dyspnea in a pediatric patient[J]. Int J Pediatr Otorhinolaryngol, 2019, 125: 164-167. DOI: 10.1016/j.ijporl.2019.07.017.
[5]	张彤, 王丽华, 高子芬, 等. 伴惰性T淋巴母细胞增生的Castleman病2例并文献复习[J]. 诊断病理学杂志, 2023, 30(7): 630-634. DOI: 10.3969/j.issn.1007-8096.2023.07.002.
[6]	刘明新, 高莹, 崔京淑, 等. 颈部Castleman病合并结节性甲状腺肿1例[J]. 临床与实验病理学杂志, 2023, 39(4): 503-504. DOI: 10.13315/j.cnki.cjcep.2023.04.029.
[7]	高焱平, 丁大帅, 谭佳帅, 等. 腹膜后Castleman病2例报告并文献复习[J]. 现代泌尿生殖肿瘤杂志, 2024, 16(2): 117-119. DOI:10.3870/j.issn.1674-4624.2024.02.013.
[8]	杨顺, 戴哲浩. 胸椎椎管内外单中心型Castleman病1例报道[J]. 实用骨科杂志, 2023, 29(5): 472-473. DOI: 10.13795/j.cnki.sgkz.2023.05.014.
[9]	高雨菡, 李剑, 张路. 特发性多中心型Castleman病发病机制的研究进展[J]. 中国医学科学院学报, 2024, 46(5): 756-762. DOI: 10.3881/j.issn.1000-503X.16008.
[10]	杨超, 张志永. 腹膜后肾区Castleman病3例临床分析[J]. 福建医科大学学报, 2022, 56(4): 368-372. DOI: 10.3969/j.issn.1672-4194.2022.04.018.
[11]	Fajgenbaum DC, Shilling D. Castleman disease pathogenesis[J]. Hematol Oncol Clin North Am, 2018, 32(1): 11-21. DOI: 10.1016/j.hoc.2017.09.002.
[12]	Wu D, Lim MS, Jaffe ES. Pathology of Castleman disease[J]. Hematol Oncol Clin North Am, 2018, 32(1): 37-52. DOI: 10.1016/j.hoc.2017.09.004.
[13]	石梦晗, 刘婉莹, 余莉. Castleman病的临床病理特征及可能的发病机制[J]. 中国肿瘤临床, 2020, 47(13): 677-681. DOI: 10.3969/j.issn.1000-8179.2020.13.599.
[14]	郭美玉, 董玉君. Castleman病研究进展[J]. 临床血液学杂志, 2022, 35(7): 534-538. DOI: 10.13201/j.issn.1004-2806.2022.07.017.
[15]	蔡利强, 毛新峰, 陈春强, 等. 局灶性透明血管型Castleman病的CT表现与病理特点分析[J]. 浙江中西医结合杂志, 2021, 31(1): 40-43. DOI: 10.3969/j.issn.1005-4561.2021.01.012.
[16]	朱军强, 尚发展, 吕秀花, 等. Castleman病的CT表现特征[J]. 现代医用影像学, 2022, 31(8): 1408-1411. DOI: 10.3969/j.issn.1006-7035.2022.08.005.
[17]	葛明, 涂丹丹, 刘振宇, 等. 透明血管型局限性Castleman病CT、MRI特征及误诊分析[J]. 实用放射学杂志, 2019, 35(10): 1644-1647. DOI: 10.3969/j.issn.1002-1671.2019.10.022.
[18]	铁宁. Castleman病的诊断及治疗进展[J]. 内蒙古医科大学学报, 2020, 42(5): 542-547. DOI: 10.16343/j.cnki.issn.2095-512x.2020.05.027.
[19]	常玉, 李文生, 孙瑞芳. Castleman病与淋巴瘤相关性研究进展[J]. 现代肿瘤医学, 2022, 30(10): 1883-1886. DOI: 10.3969/j.issn.1672-4992.2022.10.034.
[20]	中华医学会血液学分会淋巴细胞疾病学组, 中国抗癌协会血液肿瘤专业委员会, 中国Castleman病协作组. 中国Castleman病诊断与治疗专家共识(2021年版)[J]. 中华血液学杂志, 2021, 42(7): 529-534. DOI: 10.3760/cma.j.issn.0253-2727.2021.07.001.
[21]	van Rhee F, Oksenhendler E, Srkalovic G, et al. International evidence-based consensus diagnostic and treatment guidelines for unicentric Castleman disease[J]. Blood Adv, 2020, 4(23): 6039-6050. DOI: 10.1182/bloodadvances.2020003334.
[22]	顾史洋, 魏征, 季丽莉, 等. Castleman病临床诊治分析[J]. 中国临床医学, 2022, 29(4): 610-614. DOI: 10.12025/j.issn.1008-6358.2022.20211763.
[23]	贾鸣男, 张路, 李剑. 特发性多中心型Castleman病的诊疗进展[J]. 中国肿瘤临床, 2019, 46(11): 541-545. DOI: 10.3969/j.issn.1000-8179.2019.11.499.
[24]	Zhang E, Li Y, Lang N. Case report: Castleman's disease involving the renal sinus resembling renal cell carcinoma[J]. Front Surg, 2022, 9: 1001350. DOI: 10.3389/fsurg.2022.1001350.
[25]	Guo XW, Jia XD, Shen SS, et al. Radiologic features of Castleman's disease involving the renal sinus: a case report and review of the literature[J]. World J Clin Cases, 2019, 7(8): 1001-1005. DOI: 10.12998/wjcc.v7.i8.1001.

[1]	邹霞, 贺青卿, 凡庆东, 张毅, 姜军. 腋窝淋巴结Castleman病1例[J/OL]. 中华乳腺病杂志(电子版), 2007, 01(03): 20-23.
[2]	苟加梅, 陈琴, 刘旭, 周青, 吴昊, 唐杰露. Castleman病超声特征和临床分型与病理对照分析研究[J/OL]. 中华消化病与影像杂志(电子版), 2021, 11(05): 196-199.
[3]	朱旦华, 卢放根. 以腹水为主要特征的Castleman病16例[J/OL]. 中华临床医师杂志(电子版), 2024, 18(05): 462-473.
[4]	赵酉璐, 王文生, 岑溪南, 王茫桔, 孙玉华, 任汉云. 表现为POEMS综合征的Castleman病伴肾损害一例并文献复习[J/OL]. 中华临床医师杂志(电子版), 2017, 11(17): 2206-2210.
[5]	杜鹏宇, 朱红红, 孙冰, 冉启玉, 孔蕾. 特发性多中心型Castleman病的诊断学特征并文献复习[J/OL]. 中华诊断学电子杂志, 2022, 10(01): 63-66.
[6]	宋敏, 苏娜, 刘艳, 蒋胜华, 姜鲁宁. 多中心Castleman病的临床诊断学特征并文献复习[J/OL]. 中华诊断学电子杂志, 2017, 05(01): 55-58.
[7]	王新桥, 马超英, 张旭光. 纵隔单中心型Castleman病诊治体会及文献复习[J/OL]. 中华胸部外科电子杂志, 2023, 10(03): 183-187.
[8]	丁政, 李向楠, 赵佳, 朱登彦, 吴恺, 赵松. 胸内巨大淋巴结增生症的外科诊疗分析[J/OL]. 中华胸部外科电子杂志, 2015, 02(04): 254-258.

阅读次数

全文

摘要

选择文件类型/文献管理软件名称

选择包含的内容

A case report of Castleman Disease in the renal sinus

模态框（Modal）标题

选择文件类型/文献管理软件名称

选择包含的内容

A case report of Castleman Disease in the renal sinus