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中华腔镜泌尿外科杂志(电子版) ›› 2019, Vol. 13 ›› Issue (06) : 382 -386. doi: 10.3877/cma.j.issn.1674-3253.2019.06.006

所属专题: 经典病例 文献

病例研究

腹壁下静脉-精索静脉分流术治疗男性胡桃夹综合征不育患者的疗效观察
刘立民1,(), 那万里2, 曲立成3   
  1. 1. 132011 吉林市中心医院泌尿外科
    2. 130033 长春,吉林大学中日联谊医院泌尿外科
    3. 130021 长春,吉林大学第一医院生殖医学中心
  • 收稿日期:2019-07-03 出版日期:2019-12-01
  • 通信作者: 刘立民
  • 基金资助:
    吉林省卫生厅项目(3D511BB03430)

Microsurgical spermatic-inferior epigastric vein anastomosis for the treatment of nutcracker syndrome associated varicocele in infertile men

Limin Liu1,(), Wanli Na2, Licheng Qu3   

  1. 1. Department of Urology, Jilin Central Hospital, Jilin 132011, China
    2. Department of Urology, China-Japan Union Hospital of Jilin Uniersity, Changchun 130033, China
    3. Centre for Reproductive Medicine, the First Affiliated Hospital of Jilin Uniersity, Changchun 130021, China
  • Received:2019-07-03 Published:2019-12-01
  • Corresponding author: Limin Liu
  • About author:
    Corresponding author: Liu Limin, Email:
引用本文:

刘立民, 那万里, 曲立成. 腹壁下静脉-精索静脉分流术治疗男性胡桃夹综合征不育患者的疗效观察[J]. 中华腔镜泌尿外科杂志(电子版), 2019, 13(06): 382-386.

Limin Liu, Wanli Na, Licheng Qu. Microsurgical spermatic-inferior epigastric vein anastomosis for the treatment of nutcracker syndrome associated varicocele in infertile men[J]. Chinese Journal of Endourology(Electronic Edition), 2019, 13(06): 382-386.

目的

探讨显微镜下腹壁下静脉-精索静脉分流术治疗男性胡桃夹综合征患者的疗效。

方法

我们收集了2015年9月至2018年3月,吉林大学中日联谊医院8例伴有胡桃夹综合征导致的精索静脉曲张的男性不育患者的临床资料。8例患者均为体型瘦高的男性青年,平均年龄为28.5岁,其中血尿患者6例,腰痛患者1例,全部患者精子质量低下。全部患者都接受了显微镜下腹壁下静脉-精索静脉分流术的治疗。比较术前及术后的左肾静脉峰值流速比(PV比)、精子平均数量及活率、术后自然受孕率。

结果

手术时间85~105 min,术后平均住院时间为(7±0.5)d。术后随访1年,血尿消失的患者5例(83.3%),1例腰痛的患者症状缓解。术后PV比值较术前显著降低(P<0.01)。术后3、6、12个月精子总数较术前显著提高(P<0.05)。术后3、6、12个月精子活率较术前显著提高(P<0.05)。75%的患者配偶(6/8)在术后自然受孕。

结论

显微镜下精索静脉-腹壁下静脉分流术治疗伴有胡桃夹综合征导致的精索静脉曲张男性不育患者是一种安全有效的手术方式。

Objective

To assess the therapeutic effectiveness of microsurgical spermatic-inferior epigastric vein anastomosis for the treatment of nutcracker syndrome (NCS)-associated varicocele in infertile men.

Methods

We prospectively analyzed eight infertile men with NCS-associated varicocele between September 2015 and March 2018. All patients were tall young males, the average age was 28.5 years, 6 cases with hematuria, 1 cases with flank pain, all the patients showed poor sperm quality. All patients underwent microsurgical spermatic-inferior epigastric vein anastomosis. The peak flow velocity ratio before and after operation, the average number of sperm and living rate, the natural pregnancy rate after operation were compared between the two groups.

Results

The operation time was 85-105 min, and the mean postoperative hospital stay was (7.0±0.5) d. During 1-year follow-up, hematuria completely resolved in 83.3%(5/6) patients and flank pain resolved in the patient. The peak velocity ratio of postoperation significantly smaller than that of preoperation (P<0.01). The mean sperm count, respectively 3, 6, 12 months after operation was significantly higher than that of preoperation (P<0.05). The mean sperm motility, respectively 3, 6, 12 months after operation was significantly higher than that of preoperation (P<0.01). Overall, 75%(6/8) of spouses of patients went on to conceive naturally.

Conclusion

Microsurgical spermatic-inferior epigastric vein anastomosis is a safe and efficient surgical treatment for infertile men with NCS-associated varicocele.

表1 术前、术后PV1、PV2及PV比值的变化(±s)
表2 术前、术后精子数量、精子活率的变化(±s)
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