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中华腔镜泌尿外科杂志(电子版) ›› 2022, Vol. 16 ›› Issue (02) : 173 -176. doi: 10.3877/cma.j.issn.1674-3253.2022.02.017

病例研究

Zinner综合征一例报告并文献复习
倪大伟1, 魏灿1, 齐伟1, 马立山2, 张艳斌1,()   
  1. 1. 230011 安徽,合肥市第二人民医院泌尿外科
    2. 230011 合肥,安徽医学高等专科学校
  • 收稿日期:2020-12-14 出版日期:2022-04-01
  • 通信作者: 张艳斌
  • 基金资助:
    合肥市卫计委应用医学研究项目(hwk2018zd003)

Zinner syndrome: A case report and literatures review

Dawei Ni1, Can Wei1, Wei Qi1, Lishan Ma2, Yanbin Zhang1,()   

  1. 1. Department of Urology, the Second People's Hospital of Hefei, Anhui 230011, China
    2. Anhui Medical College, Hefei 230011,China
  • Received:2020-12-14 Published:2022-04-01
  • Corresponding author: Yanbin Zhang
引用本文:

倪大伟, 魏灿, 齐伟, 马立山, 张艳斌. Zinner综合征一例报告并文献复习[J]. 中华腔镜泌尿外科杂志(电子版), 2022, 16(02): 173-176.

Dawei Ni, Can Wei, Wei Qi, Lishan Ma, Yanbin Zhang. Zinner syndrome: A case report and literatures review[J]. Chinese Journal of Endourology(Electronic Edition), 2022, 16(02): 173-176.

目的

报告1例Zinner综合征病例,分析其诊治经过,并复习相关文献,提高对于本病的认识。

方法

回顾性分析1例Zinner综合征病例,患者为18岁男性,因"反复尿频、尿痛、会阴区疼痛不适1年,加重伴发热1 d"入院。经影像学及实验室检查诊断为Zinner综合征。

结果

入院后给予抗感染治疗7 d后临床症状消失,血常规、降钙素原、C反应蛋白感染指标正常,继续抗感染治疗1周出院。3个月后再次入院复查有轻度尿频,无尿痛症状,检查血常规无异常。行腹腔镜下左侧精囊囊肿切除术,术后病理明确精囊囊肿壁炎症浸润。术后5 d顺利出院。术后6个月内随访尿频、尿痛、会阴区疼痛等不适症状未再发。

结论

彩超、CT、MRI检查是诊断Zinner综合征的重要手段,病理检查是明确精囊囊肿炎症浸润的依据。急性精囊囊肿感染伴同侧肾缺如、输尿管发育畸形是Zinner综合征的表现形式之一,感染控制后行腹腔镜精囊囊肿切除术安全有效。

Objective

To report a case of Zinner syndrome, analyze its diagnosis and treatment, and review relevant literatures to improve the understanding of this disease.

Methods

A case of Zinner syndrome was retrospectively analyzed. The patient was an 18-year-old male who was admitted to our hospital due to "repeated urinary frequency, dysuria, pain and discomfort in the perineal area for 1 year, aggravation in symptom and fever for 1 day" . Zinner syndrome was diagnosed by imaging and laboratory examination.

Results

After receiving anti-infection treatment for 7 days, the clinical symptoms disappeared. Blood routine, procalcitonin and CRP infection indexes were normal, and the patient was discharged after continued anti-infection treatment for 1 week. After 3 months, the patient was re-admitted to the hospita for re-examination with mild urination frequency, no symptoms of urination pain, and no abnormalities in blood routine examination. Laparoscopic left seminal vesicle cystectomy was performed, and then postoperative pathology confirmed the inflammatory infiltration of the seminal vesicle wall. The patient was discharged from hospital 5 days after the operation. The patient was followed up 6 months after the operation without recurrence of discomfort symptoms such as frequent urination, painful urination and perineal pain.

Conclusion

Color ultrasound, CT and MRI examinations are important for the diagnosis of Zinner syndrome, and pathological examination is the basis to identify the inflammatory infiltration of seminal vesicle cyst. Acute seminal vesicle cyst infection with ipsilateral renal absence and ureteral dysplasia is one of the manifestations of Zinner syndrome. Laparoscopic seminal vesicle cystectomy after infection control is safe and effective.

图3 条索横切面光镜图(200×,HE)
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