探讨经阴道超声测量膀胱壁（BWT）、逼尿肌壁厚度（DWT）与老年女性膀胱过度活动症（OAB）相关性。

选取2021年12月至2022年5月在上海交通大学医学院附属新华医院崇明分院泌尿外科门诊就诊的80例具有尿频、尿急症状的老年女性患者作为观察组，均行压力-流率测定（PFS），根据OAB评分（OABSS）进行病情分级，并观察其PFS过程中是否出现逼尿肌过度活动（DO）和尿失禁（UI），另选取同期来我院行健康体检的健康老年女性80例作为对照组。分析超声测量BWT、DWT与OAB的关系。

观察组超声测量BWT、DWT值明显高于对照组，差异具有统计学意义（P<0.001）。BWT和DWT值均随着病情程度的升高而升高（P<0.001）；超声测量BWT与DWT值与OABSS均呈正相关（r=0.627，0.556，P<0.005）。经PFS检测，80例OAB患者中伴有UI者23例，不伴有UI者57例，伴有DO（OAB-DO）的患者有31例，单纯OAB患者49例。伴有UI的OAB患者BWT和DWT值均高于不伴有UI的OAB患者（P<0.05）。OAB-DO患者BWT和DWT值均高于单纯OAB患者（P<0.001）；超声测量BWT、DWT均具有诊断OAB-DO的价值（P<0.05），其AUC分别为0.668，0.713；此时BWT截断值分别为5.91 mm，敏感度为41.94%，特异度为89.80%；DWT截断值为2.52 mm，敏感度为51.61%，特异度为97.96%。31例OAB-DO患者中伴有UI的21例，不伴有UI的10例。伴有UI的OAB-DO患者BWT和DWT值均高于单纯OAB-DO患者（P<0.05）。

经阴道超声是一种可靠且侵入性较小的检查方式，可直接对BWT、DWT值进行测量，对评估老年女性OAB病情具有一定的临床价值。

To explore the correlation between bladder wall thickness (BWT) and detrusor wall thickness (DWT) measured by transvaginal ultrasound and overactive bladder (OAB) in elderly women.

A total of 80 elderly female patients with frequent urination and urinary urgency treated in Urology outpatient of Chongming Branch of Xinhua Hospital Affiliated to Shanghai Jiaotong University were enrolled as observation group from December 2021 to May 2022. All patients underwent pressure-flow study (PFS). The conditions of patients were graded according to OAB symptom score (OABSS). The presence or absence of detrusor overactivity (DO) and urinary incontinence (UI) in PFS process was observed. A total of 80 healthy elderly women undergoing physical examination during the same period were enrolled as control group. The relationship between BWT, DWT and OAB was analyzed.

BWT and DWT in observation group were significantly thicker than those in control group (P<0.001). With the aggravation of disease severity, BWT and DWT were increased (P<0.001). BWT and DWT were positively correlated with OABSS (r=0.627, 0.556, P<0.005). PFS showed that among the 80 patients OAB, there were 23 cases with UI and 57 cases without, 31 cases with DO and 49 cases without. The BWT and DWT values of patients with UI were higher than those of patients without (P<0.05). BWT and DWT in OAB-DO patients were thicker than those without DO (P<0.05). BWT and DWT were of diagnosing value for OAB-DO (P<0.05), the AUC values were 0.668 and 0.713, respectively. The cut-off value, sensitivity and specificity of BWT and DWT were (5.91 mm, 41.94%, 89.80%) and (2.52mm, 51.61%, 97.96%), respectively. There were 21 cases with UI and 10 cases without in 31 patients of OAB-DO. The BWT and DWT values of patients of OAB-DO with UI were higher than those of patients without UI (P<0.05).

Transvaginal ultrasonography is a reliable diagnostic method, with low invasion. It can directly measure BWT and DWT, which has certain clinical evaluation value for the severity of OAB in elderly women.