库欣综合征（CS）和嗜铬细胞瘤及副神经节瘤（PPGL）均为内分泌肿瘤，可引起体内相关肾上腺激素失调，合并妊娠时，会导致孕期母婴并发症的风险明显增加，且围手术期手术风险极高。本文报告3 例病例，包括2 例妊娠合并CS，1 例妊娠合并PPGL，并对相关文献进行回顾。3 例患者均于妊娠中晚期行腹腔镜手术治疗，术中、术后均未出现并发症。2 例CS 患者术后给予激素替代治疗，3 例患者术后随访预后良好。妊娠合并CS 和PPGL 较为罕见，手术风险极高，围手术期充分准备后可于妊娠中晚期行腹腔镜手术治疗。

Objective

Cushing's syndrome （CS） and pheochromocytoma and paraganglioma （PPGL）are both endocrine tumors that can lead to dysregulation of adrenal hormones.When these conditions occur during pregnancy，they significantly increase the risk of maternal and fetal complications，and the perioperative surgical risks are exceptionally high.In this report，we present three cases： two of pregnancy complicated by CS and one complicated by PPGL，accompanied by a review of relevant literature.All three patients underwent laparoscopic surgery in the late second or third trimester，without any complications during or after the procedure.The two CS patients received hormone replacement therapy postoperatively，and all three patients demonstrated favorable outcomes during follow-up.Although pregnancy complicated by CS and PPGL is relatively rare and poses substantial surgical risks，laparoscopic surgery can be safely performed in the late stages of pregnancy with appropriate perioperative preparation.