探讨前列腺肉瘤的临床表现、影像学特点、病理特征、治疗方法和临床预后。

回顾分析1999年1月至2019年12月收治的12例前列腺肉瘤患者的临床资料，总结分析前列腺肉瘤的临床病理特点，治疗方式及预后。

12例患者均行超声引导下经直肠前列腺穿刺活检，病理结果为前列腺肉瘤，其中横纹肌肉瘤6例，平滑肌肉瘤3例，未分化肉瘤2例，癌肉瘤1例。2例行根治性膀胱前列腺切除术+回肠代膀胱术，5例行根治性前列腺切除术；3例行放化疗；1例仅行化疗，1例仅行前列腺穿刺活检。12例患者除1例仍在随访外均因肿瘤复发转移死亡，平均生存时间15个月（8～25个月）。

前列腺肉瘤恶性程度较高，预后差，超声引导下前列腺穿刺活检和MRI有助于明确诊断，确诊主要依靠病理检查，治疗方法以手术为主，辅以放化疗等综合治疗。

To investigate the clinical characteristics, imaging and pathological features, treatment and prognosis of primary prostate sarcoma in adults.

A retrospective analysis was performed on the clinical data of 12 patients with primary prostate sarcoma from January 1999 to December 2019 in the First Affiliated Hospital of Sun Yat-Sen University.

12 patients were diagnosed as prostate sarcoma by trans-rectal ultrasound prostate (TRUS-biopsy), pathological diagnosis revealed that 6 cases with rhabdomyosarcoma, 3 cases with leiomyosarcoma, 2 cases with undifferentiated sarcoma and 1 cases with carcinoid sarcoma. 2 patients received radical cystoprostatectomy and Bricker operation, 5 patients received radical prostatectomy, 2 patients received chemotherapy and radiotherapy, 1 patients received just chemotherapy, 1 patients just underwent prostate biopsy. And postoperative follow-up was performed.They all experienced recurrence and died as a result of disease progression except one patient who is still under follow-up. The average survival time was 15 months.

Prostate sarcoma is rare and highly malignant. The diagnosis is confirmed by TRUS-biopsy and MRI. Surgery remains the main treatment option, chemotherapy and radiotherapy provide therapeutic benefits.