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中华腔镜泌尿外科杂志(电子版) ›› 2021, Vol. 15 ›› Issue (04) : 343 -346. doi: 10.3877/cma.j.issn.1674-3253.2021.04.017

病例研究

婴儿腹腔镜肾上腺皮质癌根治术一例报道并文献复习
叶雷1, 马波1, 朱顺叶2, 钟文文1, 郭强1, 瞿虎1, 尧冰1, 汪中扬1, 王德娟1,(), 邱剑光1   
  1. 1. 510655 广州,中山大学附属第六医院泌尿外科
    2. 510630 广州,中山大学附属第三医院儿科
  • 收稿日期:2020-06-24 出版日期:2021-08-01
  • 通信作者: 王德娟
  • 基金资助:
    广东省自然科学基金(2019A1515010386)

Laparoscopic radical resection of adrenocortical carcinoma in an infant: a case report and literature review

Lei Ye1, Bo Ma1, Shunye Zhu2, Wenwen Zhong1, Qiang Guo1, Hu Qu1, Bing Yao1, Zhongyang Wang1, Dejuan Wang1,(), Jianguang Qiu1   

  1. 1. Department of Urology, the Sixth Affiliated Hospital of Sun Yat-sen University, Guangzhou 510655, China
    2. Department of Pediatrics, the Third Affiliated Hospital, Sun Yat-sen University, Guangzhou 510630, China
  • Received:2020-06-24 Published:2021-08-01
  • Corresponding author: Dejuan Wang
引用本文:

叶雷, 马波, 朱顺叶, 钟文文, 郭强, 瞿虎, 尧冰, 汪中扬, 王德娟, 邱剑光. 婴儿腹腔镜肾上腺皮质癌根治术一例报道并文献复习[J/OL]. 中华腔镜泌尿外科杂志(电子版), 2021, 15(04): 343-346.

Lei Ye, Bo Ma, Shunye Zhu, Wenwen Zhong, Qiang Guo, Hu Qu, Bing Yao, Zhongyang Wang, Dejuan Wang, Jianguang Qiu. Laparoscopic radical resection of adrenocortical carcinoma in an infant: a case report and literature review[J/OL]. Chinese Journal of Endourology(Electronic Edition), 2021, 15(04): 343-346.

目的

报道1例婴儿肾上腺皮质癌诊治经过,增加对该疾病的认识。

方法

回顾分析近期我院的1例9个月婴儿肾上腺皮质癌的临床资料,并对相关文献进行分析总结,归纳小儿肾上腺皮质癌的临床特点。

结果

本例患儿出现明确的内分泌功能改变及儿童性早熟体征。行腹腔镜右侧肾上腺皮质癌根治术,肿瘤完整切除,未见周围及远处转移,术后1年复诊时未见复发,病态外观恢复正常。

结论

婴儿肾上腺皮质癌在小儿肿瘤中罕见,但具有较典型的内分泌功能改变后的临床外观变化。对小儿肾上腺皮质癌的诊断应经过充分评估,通过患儿的临床表现、内分泌情况、影像学结果以及病理学结果综合判断。首选治疗为手术完整切除肿瘤,可以辅助密妥坦药物治疗等多种治疗方案。

Objective

To discuss the diagnosis and treatment characteristics of adrenocortical carcinoma (ACC) in children, so as to increase the knowledge of the disease.

Methods

The clinical data of a case with pediatric ACC in the Sixth Affiliated Hospital were analyzed retrospectively. The clinical characteristics of ACC in children were summarized.

Results

This infant showed typical pathological changes in appearance. Laparoscopic radical resection of right adrenocortical carcinoma was performed. The tumor was completely resected and no peripheral or distant metastasis was found. There was no recurrence when the child was followed one year after the operation, and the pathological appearance recovered.

Conclusion

Pediatric ACC is rare even in pediatric tumors, but it has a typical clinical appearance after endocrine function changes. The diagnosis of ACC in children should be fully evaluated, based on comprehensive judgment of the child's clinical manifestations, endocrine conditions, imaging results and pathological results. The first choice of treatment is complete surgical resection of the tumor, which can assist with various treatment options such as mitotane therapy.

图1 9个月肾上腺皮质癌患儿术前资料
图2 肾上腺皮质癌患儿术后相关情况
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