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中华腔镜泌尿外科杂志(电子版)

中华腔镜泌尿外科杂志(电子版) ›› 2024, Vol. 18 ›› Issue (05) : 520 -524. doi: 10.3877/cma.j.issn.1674-3253.2024.05.017

综述

术中输尿管识别技术研究进展
李佳伟1, 庞建智2, 闫鹏宇1, 卫阳兵1, 杨晓峰3,†()   
  1. 1. 030001　太原，山西医科大学第一临床医学院
    2. 山西医科大学第一医院泌尿外科
    3. 030001　太原，山西医科大学第一临床医学院；山西医科大学第一医院泌尿外科
  • 收稿日期:2023-03-02 出版日期:2024-10-01
  • 通信作者: 杨晓峰
  • 基金资助:
    中央引导地方科技发展资金项目(YPZJSX2021C010)

Research progress of intraoperative ureteral identification technology

Jiawei Li1, Jianzhi Pang2, Pengyu Yan1, Yangbing Wei1, Xiaofeng Yang3,†()   

  1. 1. The First Clinical College of Shanxi Medical University, Taiyuan 030001, China
    2. Department of Urology, The First Hospital of Shanxi Medical University, Taiyuan 030001, China
    3. The First Clinical College of Shanxi Medical University, Taiyuan 030001, China; Department of Urology, The First Hospital of Shanxi Medical University, Taiyuan 030001, China
  • Received:2023-03-02 Published:2024-10-01
  • Corresponding author: Xiaofeng Yang
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李佳伟, 庞建智, 闫鹏宇, 卫阳兵, 杨晓峰. 术中输尿管识别技术研究进展[J]. 中华腔镜泌尿外科杂志(电子版), 2024, 18(05): 520-524.

Jiawei Li, Jianzhi Pang, Pengyu Yan, Yangbing Wei, Xiaofeng Yang. Research progress of intraoperative ureteral identification technology[J]. Chinese Journal of Endourology(Electronic Edition), 2024, 18(05): 520-524.

由于输尿管解剖结构的特殊性，在腹盆腔手术中易发生输尿管损伤。医源性输尿管损伤将会产生一系列严重的并发症。因此，术中输尿管识别和保护技术被广泛研究以降低术中输尿管损伤的发生率。分析国内外研究进展，术中输尿管识别技术包括非荧光示踪技术和荧光示踪技术两类。其中荧光示踪技术的研究较为深入，主要的荧光示踪剂包括荧光素钠、亚甲蓝、吲哚菁绿、IRDye800系列、ZW800-1和IS-001等。由于荧光示踪技术可以实现术中输尿管实时可视化，因此其在术中输尿管识别和保护中具有重要的价值和意义。

关键词: 输尿管识别, 近红外荧光, 荧光成像, 输尿管支架, 荧光素钠, 亚甲蓝, 吲哚菁绿, 荧光染料/荧光示踪剂

Due to the particularity of the anatomical structure of the ureter, ureteral injury is prone to occur in pelvic surgery. Irogenic ureteral injury will cause a series of serious complications. Therefore, intraoperative ureteral recognition and protection technology has been widely studied to reduce the incidence of intraoperative ureteral injury. Based on the analysis of the research progress at home and abroad. Intraoperative ureter recognition technology includes non-fluorescent tracer technology and fluorescence tracer technology. Among them, fluorescence tracer technology has been deeply studied. The main fluorescent tracers include sodium fluorescein, methylene blue, indocyanine green, IRDye800-CA, ZW800-1 and IS-001. Because fluorescence tracer technology can realize real-time visualization of intraoperative ureter, it has important value and significance in intraoperative ureter recognition and protection.

Key words: Ureteral recognition, Near-ir fluorescence, Fluorescence imaging, Ureteral stent, Sodium fluorescein, Methylene blue, indocyanine green, Fluorochrome/Fluorescent tracer
[1]
孙凌宇,白明瀚,郑宏群.腹腔镜结直肠手术中输尿管及尿道损伤的预防及处理[J].中国实用外科杂志, 2022, 42(11): 1256-1259.
[2]
Joshua S. Ureteral Injury[M] .Treasure Island (FL): StatPearls Publishing, 2022.
[3]
Misal M, Dizon AM, Louie M, et al. Risk of urinary tract infection symptoms after posthysterectomy cystoscopy with 50% dextrose as compared with saline cystoscopy with indigo carmine[J]. J Minim Invasive Gynecol, 2021, 28(2): 282-287.
[4]
王宇伟. 医源性输尿管损伤的防治分析[D]. 杭州: 浙江中医药大学, 2022.
[5]
Shahait AD, Mesquita-Neto JW B, Girten K, et al. Iatrogenic ureteral injury and prophylactic stent use in veterans undergoing colorectal surgery[J]. J Surg Res, 2021, 265: 272-277.
[6]
Chahin F, Dwivedi A J, Paramesh A, et al. The implications of lighted ureteral stenting in laparoscopic colectomy[J]. JSLS, 2002, 6(1): 49-52.
[7]
田华, 宋越. 妇科腔镜术中医源性输尿管损伤预防研究进展[J]. 临床军医杂志, 2019, 47(7): 768-770.
[8]
Ryu S, Okamoto A, Nakashima K, et al. Ureteral navigation using a fluorescent ureteral catheter during laparoscopic colorectal surgery[J]. Surg Endosc, 2021, 35(8): 4882-4889.
[9]
Zarifmahmoudi L, Ghorbani H, Sadeghi R, et al. Sentinel lymph node biopsy in upper tract urothelial cancers: an experience with intraoperative radiotracer injection[J]. Nucl Med Rev Cent East Eur, 2021, 24(2): 41-45.
[10]
Berland TL, Smith SL, Metzger PP, et al. Intraoperative gamma probe localization of the ureters: a novel concept[J]. J Am Coll Surg, 2007, 205(4): 608-611.
[11]
黄陆茂, 辛学刚. 腹部术中输尿管实时识别研究进展[J]. 分子影像学杂志, 2018, 41(2): 189-195.
[12]
Dip FD, Nahmod M, Anzorena FS, et al. Novel technique for identification of ureters using sodium fluorescein[J]. Surg Endosc, 2014, 28(9): 2730-2733.
[13]
Slooter MD, Janssen A, Bemelman WA, et al. Currently available and experimental dyes for intraoperative near-infrared fluorescence imaging of the ureters: a systematic review[J]. Tech Coloproctol, 2019, 23(4): 305-313.
[14]
Malhotra C, Pawar R, Patni S, et al. Efficacy of periareolar versus peritumoral injection of TC99-labelled sulphur colloid and methylene blue dye for detection of sentinel lymph node in patients with early breast cancer: a comparative study[J]. Indian J Surg Oncol, 2021, 12(1): 119-123.
[15]
吴德庆, 杨悦生, 张维富, 等. 静脉滴注亚甲蓝溶液在腹腔镜下结直肠外科术中输尿管显影中的应用[J]. 中华胃肠外科杂志, 2022, 25(12): 1098-1103.
[16]
Barnes TG, Hompes R, Birks J, et al. Methylene blue fluorescence of the ureter during colorectal surgery[J]. Surg Endosc, 2018, 32(9): 4036-4043.
[17]
Polom W, Migaczewski M, Skokowski J, et al. Multispectral imaging using fluorescent properties of indocyanine green and methylene blue in colorectal surgery-initial experience[J]. J Clin Med, 2022, 11(2): 368.
[18]
Usefzay O, Yari S, Amiri P, et al. Evaluation of protective effects of methylene blue on cisplatin-induced nephrotoxicity[J]. Biomedecine Pharmacother, 2022, 150: 113023.
[19]
Visclosky T, Schaeffer W, Pomeranz E, et al. Primaquine overdose in a toddler[J]. Am J Emerg Med, 2021, 45: 676.e3-676676.e5.
[20]
Korb ML, Huh WK, Boone JD, et al. Laparoscopic fluorescent visualization of the ureter with intravenous IRDye800CW[J]. J Minim Invasive Gynecol, 2015, 22(5): 799-806.
[21]
van den Bos J, Al-Taher M, Bouvy ND, et al. Near-infrared fluorescence laparoscopy of the ureter with three preclinical dyes in a pig model[J]. Surg Endosc, 2019, 33(3): 986-991.
[22]
de Valk KS, Handgraaf HJ, Deken MM, et al. A zwitterionic near-infrared fluorophore for real-time ureter identification during laparoscopic abdominopelvic surgery[J]. Nat Commun, 2019, 10(1): 3118.
[23]
Ahn CB, Kim JH, Park GK, et al. Prognostic imaging of iatrogenic and traumatic ureteral injury by near-infrared fluorescence[J]. Quant Imaging Med Surg, 2019, 9(6): 1056-1065.
[24]
Farnam RW, Arms RG, Klaassen AH, et al. Intraoperative ureter visualization using a near-infrared imaging agent[J]. J Biomed Opt, 2019, 24(6): 1-8.
[25]
Soriano CR, Cheng RR, Corman JM, et al. Feasibility of injected indocyanine green for ureteral identification during robotic left-sided colorectal resections[J]. Am J Surg, 2022, 223(1): 14-20.
[26]
Friedman-Levi Y, Larush L, Diana M, et al. Optimization of liposomal indocyanine green for imaging of the urinary pathways and a proof of concept in a pig model[J]. Surg Endosc, 2018, 32(2): 963-970.
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