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中华腔镜泌尿外科杂志(电子版) ›› 2023, Vol. 17 ›› Issue (03) : 201 -208. doi: 10.3877/cma.j.issn.1674-3253.2023.03.001

所属专题: 指南共识

专家共识

前列腺癌骨转移诊疗专家共识(2023版)
南方护骨联盟前列腺癌骨转移专家组   
  • 收稿日期:2023-02-21 出版日期:2023-06-01
  • 基金资助:
    国家自然科学基金青年项目(8220102126)

Expert consensus on the diagnosis and treatment of bone metastasis in prostate cancer (2023 edition)

Southern Bone Protection Alliance Prostate Cancer Bone Metastasis Expert Group   

  • Received:2023-02-21 Published:2023-06-01
引用本文:

南方护骨联盟前列腺癌骨转移专家组. 前列腺癌骨转移诊疗专家共识(2023版)[J]. 中华腔镜泌尿外科杂志(电子版), 2023, 17(03): 201-208.

Southern Bone Protection Alliance Prostate Cancer Bone Metastasis Expert Group. Expert consensus on the diagnosis and treatment of bone metastasis in prostate cancer (2023 edition)[J]. Chinese Journal of Endourology(Electronic Edition), 2023, 17(03): 201-208.

骨是前列腺癌最常见的转移部位,骨转移占所有前列腺癌转移部位的88.7%,前列腺癌是最容易发生骨转移的恶性肿瘤之一[1]。由于我国尚未普及前列腺癌筛查,据报道54%新诊断前列腺癌患者存在骨转移[2]。另外,在死于前列腺癌的患者中,85%~100%存在骨转移[3]。前列腺血管与椎静脉丛(Batson丛)有广泛的交通,前列腺癌细胞通过血道转移至骨,因此,脊椎、骨盆、肋骨和长骨近端等部位是骨转移好发部位,以中轴骨转移为主,常为多发转移[3]。成骨性病变占到前列腺癌骨转移的95%,混合性病变占5%,单纯溶骨性转移很少见[4]。前列腺癌骨转移可导致骨相关事件(skeletal-related events,SREs),包括病理性骨折、脊髓压迫、骨外科手术、骨放射治疗(包括放射性同位素的使用)[5],部分研究将骨转移瘤引起的高钙血症和需要更换抗肿瘤治疗方案的骨痛亦归为SREs[6,7]

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