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中华腔镜泌尿外科杂志(电子版) ›› 2024, Vol. 18 ›› Issue (03) : 202 -207. doi: 10.3877/cma.j.issn.1674-3253.2024.03.001

总编专栏

2024年欧洲泌尿外科学会年会:前列腺癌研究的前沿探索与未来趋势
黄海1, 程必盛1, 黄健1,()   
  1. 1. 510260 广州,中山大学孙逸仙纪念医院泌尿外科
  • 收稿日期:2024-03-16 出版日期:2024-06-01
  • 通信作者: 黄健
  • 基金资助:
    国家重点研发计划(2022YFC3602900,2022YFC3602904); 国家自然科学基金(81974395,82173036); 广东省基础与应用基础研究基金(2019A1515011437); 广东省国际科技合作项目计划(2021A0505030085); 中山大学临床研究5010计划(2019005); 中山临床研究培育计划(201702); 广东省恶性肿瘤表观遗传和基因调控重点实验室(2020B1212060018OF006); 广东省泌尿系统疾病临床研究中心(2020B1111170006); 北京白求恩慈善基金(mnzl202001); 广州市科技重大专项(202206010117); 北京CSCO临床研究基金(Y-tongshu2021/ms-0162)

2024 Annual Meeting of European Association of Urology: frontier exploration and future trends in prostate cancer research

Hai Huang1, Bisheng Cheng1, Jian Huang1,()   

  1. 1. Department of Urology, Sun Yat-sen Memorial Hospital, Sun Yat-sen University, Guangzhou 510260, China
  • Received:2024-03-16 Published:2024-06-01
  • Corresponding author: Jian Huang
引用本文:

黄海, 程必盛, 黄健. 2024年欧洲泌尿外科学会年会:前列腺癌研究的前沿探索与未来趋势[J/OL]. 中华腔镜泌尿外科杂志(电子版), 2024, 18(03): 202-207.

Hai Huang, Bisheng Cheng, Jian Huang. 2024 Annual Meeting of European Association of Urology: frontier exploration and future trends in prostate cancer research[J/OL]. Chinese Journal of Endourology(Electronic Edition), 2024, 18(03): 202-207.

本文总结了2024年欧洲泌尿外科学会(EAU)年会中关于前列腺癌研究的重要进展和未来趋势。研究指出,分子影像学技术如前列腺特异性膜抗原正电子发射断层扫描(PSMA-PET)在前列腺癌的诊断和分期中显示出高敏感性和特异性,尽管存在技术限制和对标准化的需求。生物标志物在早期诊断和治疗决策中的作用日益重要,液体活检方法表现出高敏感性和特异性。对于PSMA阳性M1a患者的治疗策略,目前存在全身与局部治疗的争议,需要更多研究来明确最佳实践。局灶治疗作为一种减少副作用、提高生活质量的方法,适用于特定患者。营养支持对患者的整体健康和治疗反应至关重要。技术创新,包括远程监测、人工智能和电子患者报告结果(ePROMs)正在改变前列腺癌的诊断和治疗模式。未来研究将致力于优化治疗方案,创新局灶治疗技术,评估营养干预的长期效果,并进一步应用技术创新,以提高治疗效果和患者满意度。

This article summarizes the important advances and future trends in prostate cancer research presented at the 2024 European Urological Association (EAU) Annual Meeting. Studies have indicated that molecular imaging techniques such as prostate-specific membrane antigen positron emission tomography (PSMA-PET) demonstrate high sensitivity and specificity in the diagnosis and staging of prostate cancer, despite existing technical limitations and the need for standardization. The role of biomarkers in early diagnosis and treatment decision-making is becoming increasingly important, with liquid biopsy methods showing high sensitivity and specificity. There is an ongoing debate regarding the treatment strategy for PSMA-positive M1a patients, with a need for further research to clarify best practices. Focal therapy, as a method to reduce side effects and improve quality of life, is suitable for specific patients. Nutritional support is crucial for the overall health and treatment response of patients. Technological innovations, including remote monitoring, artificial intelligence (AI), and electronic patient-reported outcome measures (ePROMs), are changing the diagnostic and treatment paradigms for prostate cancer. Future research will focus on optimizing treatment plans, innovating focal therapy techniques, evaluating the long-term effects of nutritional interventions, and further applying technological innovations to improve treatment outcomes and patient satisfaction.

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