To compare the clinical data of the laparoendoscopic single-site nephrectomy(LESS) and traditional three holes laparoscopic nephrectomy, for investigating the safety and effectiveness of single-site laparoscopic in the urological utility.

The operative time, intraoperative blood loss, postoperative recovery time of intestinal ventilation, postoperative indwelling drainage tube time, postoperative hospitalization days of clinical data of 35 cases were analyzed retrospectively, 15 cases underwent single-site laparoscopic nephrectomy, and 20 cases underwent traditional laparoscopic nephrectomy (TCL).

There was no difference between the 2 groups in the age [(53±13) years old vs (51±11) years old, P=0.773], body weight[(22.1±2.6) kg/m² vs (22.7±3.3) kg/m², P=0.535], gender distribution, classification of pathology, operative access, intraoperative blood loss[(142±74) ml vs (138±60) ml, P=0.861)], recovery of intestinal ventilation [(2.0±0.7) d vs (2.0±0.6) d, P=1.000], postoperative indwelling drainage tube [(3.5±0.9) d vs (3.2±1.1) d, P=0.453] and hospital stay [(7.1±2.2) d vs (6.8±1.6) d, P=0.729]. Fourteen of the 15 patients in the LESS group underwent the procedure successfully without additional trocar placement. LESS nephrectomy took longer operative time than TLC group [(231±52) min vs (157±30) min, P<0.01). No wound infection occurred after LESS nephrectomy. No access site hernia was noted in the patients in the LESS group at short-time follow-up, and the scar was also small.

The LESS nephrectomy, whether via lumber or abdomen, is safe and effective comparable to TCL, which can satisfy the beautiful wish of patients to the incision, but the learning curve and operative time was long, with the improvement of surgical technique and the operative instruments, perhaps can effectively solve the problem.