Risk factors for urosepsis following flexible uroterescopic lithotripsy

doi:10.3877/cma.j.issn.1674-3253.2017.01.012

Abstract

Abstract:

Objective

To explore the risk factors for urosepsis following flexible uroterescopic lithotripsy.

Methods

From August 2013 to December 2014, clinical data of 187 patients underwent flexible uroterescopic lithotripsy in the First Affiliated Hospital of Xinjiang Medical University were analyzed retrospectively. A total of 21 cases with urosepsis and 166 patients without urosepsis were retrospectively analyzed by case control study to explore the risk factors. Statistically significant materials after using single factor analysis were analyzed by multivariate logistic regression method.

Results

By t-test and chi-square test analysis, urosepsis following flexible uroterescopic lithotripsy was correlated with gender, diabetes, stone burden, operative time, positive urine culture (P<0.05). Introduction of multifactor non-conditional logistic regression analysis, showed that gender (OR=0.293), stone burden (OR=1.135), and positive urine culture (OR=9.883) were the main risk factors.

Conclusion

Gender, stone burden and positive urine culture were independent risk factors of urosepsis following flexible uroterescopic lithotripsy. Patients with these high-risk factors should be highly alert and evaluate risk factors to reduce urosepsis.

Key words: Flexible uroterescopy, Urosepsis, Stone, Risk factors

Aibibuli Yusufu·, Tusong Hamulati·, Feng Wang, Maolakuerban Naibijiang·, Guanglu Song, Yujie Wang, Yasheng Anniwaer·. Risk factors for urosepsis following flexible uroterescopic lithotripsy[J]. Chinese Journal of Endourology(Electronic Edition), 2017, 11(01): 49-53.

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Figures/Tables 2

References 21

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组别	例数	年龄（岁，± s）	性别（例）		糖尿病（例）		尿培养（例）		手术时间（min，±s）
组别	例数	年龄（岁，± s）	男	女	有	无	阳性	阴性	手术时间（min，±s）
感染组	21	50±12	11	10	5	16	11	10	54±19
未感染组	166	47±15	124	42	11	155	35	131	45±12
统计值	?	t=-0.943	χ²=4.625		χ²=5.010		χ²=11.407		t=2.996
P值	?	0.347	0.043		0.021		0.001		0.003
组别	肾积水程度（mm，±s）	结石大小（mm，±s）	结石CT值（HU，±s）	血红蛋白（g/L，±s）	白蛋白[g/L，M（P25~P75）]	血肌酐[μmol/L，M（P25~P75）]	尿素氮[mmol/L，M（P25~P75）]
感染组	20±7	15±4	1024±328	135±18	134（121~147）	62（51~102）	5.5（4.2~7.3）
未感染组	20±8	12±5	827±390	139±18	142（127~153）	78（65~99）	5.4（4.4~6.7）
统计值	t=0.418	t=-2.404	t=-1.578	t=0.925	z=-1.272	z=-1.705	z=-0.357
P值	0.677	0.017	0.121	0.356	0.203	0.088	0.721

组别	例数	年龄（岁，± s）	性别（例）		糖尿病（例）		尿培养（例）		手术时间（min，±s）
组别	例数	年龄（岁，± s）	男	女	有	无	阳性	阴性	手术时间（min，±s）
感染组	21	50±12	11	10	5	16	11	10	54±19
未感染组	166	47±15	124	42	11	155	35	131	45±12
统计值	?	t=-0.943	χ²=4.625		χ²=5.010		χ²=11.407		t=2.996
P值	?	0.347	0.043		0.021		0.001		0.003
组别	肾积水程度（mm，±s）	结石大小（mm，±s）	结石CT值（HU，±s）	血红蛋白（g/L，±s）	白蛋白[g/L，M（P25~P75）]	血肌酐[μmol/L，M（P25~P75）]	尿素氮[mmol/L，M（P25~P75）]
感染组	20±7	15±4	1024±328	135±18	134（121~147）	62（51~102）	5.5（4.2~7.3）
未感染组	20±8	12±5	827±390	139±18	142（127~153）	78（65~99）	5.4（4.4~6.7）
统计值	t=0.418	t=-2.404	t=-1.578	t=0.925	z=-1.272	z=-1.705	z=-0.357
P值	0.677	0.017	0.121	0.356	0.203	0.088	0.721

变量	β值	P值	OR（95%CI）
结石大小	0.127	0.026	1.135（1.015~1.270）
手术时间	0.041	0.074	1.042（0.996~1.091）
性别（男/女）	-1.228	0.039	0.293（0.091~0.942）
糖尿病	1.229	0.11	3.419（0.757~15.443）
尿培养	2.291	0.007	9.883（1.888~51.740）

变量	β值	P值	OR（95%CI）
结石大小	0.127	0.026	1.135（1.015~1.270）
手术时间	0.041	0.074	1.042（0.996~1.091）
性别（男/女）	-1.228	0.039	0.293（0.091~0.942）
糖尿病	1.229	0.11	3.419（0.757~15.443）
尿培养	2.291	0.007	9.883（1.888~51.740）

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