To explore the clinical value of real-time three-dimensional transperineal ultrasonography in the diagnosis of perineal cystic-solid lesion.

Ultrasonographic performances of 219 female patients who were diagnosed as periurethral cystic lesions by surgical and clinical diagnosis and received perineal real-time three-dimensional ultrasonography were retrospectively analyzed, and ultrasonographic features of different perineal cystic-solid lesion were summarized.

Perineal cystic-solid lesion could be shown clearly by perineal real-time three-dimensional ultrasonography. Among the 219 patients, 33 patients with vaginal wall cysts, 7 patients with paraurethral cysts, 7 patients with urethral diverticulum, 58 patients with cystocele, 4 patients with intravaginal tumor, 32 patients with uterine prolapse, 52 patients with perineal hypermobility, and 26 patients with rectocele, vaginal wall cysts and periurethral cysts manifested as periurethral oval-like anechoic or hypoechoic area, and didn't connect with urethra and vagina. Urethral diverticulum in the sonogram echogram manifested as irregular periurethral anechoic or hypoechoic area, and connected with urethra. Intravaginal tumor manifested as irregular hypoechoic areas in the vagina. Cystocele, uterine prolapse, perineal hypermobility and rectocele manifested as the velative organs moved down under the reference line.

The real-time three-dimensional ultrasonography is effective for diagnosis and differential diagnosis of perineal cystic-solid lesion.