Clinical observation of microwave thermotherapy combined with intravesical tri-drug therapy for bladder pain syndrome/interstitial cystitis

doi:10.3877/cma.j.issn.1674-3253.2019.04.004

Abstract

Abstract:

Objective

To evaluate the efficacy of microwave thermotherapy combined with tri-drug bladder perfusion for treatment of bladder pain syndrome/interstitial cystitis (BPS/IC).

Methods

During Feb 2014 to Sep 2017, 51 BPS/IC patients were treated, including 44 women and 7 men, with mean age of 36 years, mean course of 32 months. The control group was treated with triplex drug bladder perfusion, and the study group was treated with microwave thermotherapy on the basis of bladder perfusion. O'Leary-Sant questionnaire interstitial bladder inflammation shape index and problem index score (ICSI+ICPI), pelvic pain and urinary frequency score (PUF), and visual analogue scale (VAS) were observed and recorded for IC/BPS symptom assessment before and after treatments.

Results

After the treatments, the rate of curative effect was significantly higher than that of the control group, and the difference was significant (P<0.05). ICSI, ICPI, PUF and VAS scores of study groups were improved than those of control group [(7.3±3.3) vs (10.7±2.5), (5.2±3.5) vs (7.5±3.5), (19.6±3.4) vs (22.3±4.7), (5.0±0.7)vs (5.8±1.1), all P<0.05)]. And all scores of the two groups after treatmant were improved than those before treatment. The effective rate of the treatment group was 91%, and no serious adverse reactions occurred in all patients.

Conclusions

Treating BPS/IC patients with microwave thermotherapy combined with intravesical drug therapy can effectively relieve clinical symptom.

Key words: BPS/IC, Microwave thermotherapy, Intravesical drug therapy, Curative effect

Xuelian Chen, Minzhi Su, Xiangfu Zhou, Zhen Wu, Danling Rao, Bolong Liu. Clinical observation of microwave thermotherapy combined with intravesical tri-drug therapy for bladder pain syndrome/interstitial cystitis[J]. Chinese Journal of Endourology(Electronic Edition), 2019, 13(04): 230-233.

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References 16

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组别	例数	ICSI（分，±s）		ICPI（分，±s）		PUF（分，±s）		VAS（分，±s）		改善情况（例）
组别	例数	治疗前	治疗后	治疗前	治疗后	治疗前	治疗后	治疗前	治疗后	治愈	显数	有效	无效
治疗组	24	12.7±3.8	7.3±3.3	10.6±4.1	5.2±3.5	25.0±6.4	19.6±3.4	7.2±1.3	5.0±0.7	5	9	8	2
对照组	27	12.8±4.6	10.7±2.5	10.7±3.2	7.5±3.5	25.6±3.4	22.3±4.7	6.8±1.3	5.8±1.1	3	7	10	7
统计值	0	t=0.165	t=3.972	t=0.192	t=2.521	t=0.416	t=2.273	t=1.441	t=2.774	χ²=4.694
P值	?	0.870	<0.001	0.849	0.015	0.679	0.028	0.173	0.008	0.030

组别	例数	ICSI（分，±s）		ICPI（分，±s）		PUF（分，±s）		VAS（分，±s）		改善情况（例）
组别	例数	治疗前	治疗后	治疗前	治疗后	治疗前	治疗后	治疗前	治疗后	治愈	显数	有效	无效
治疗组	24	12.7±3.8	7.3±3.3	10.6±4.1	5.2±3.5	25.0±6.4	19.6±3.4	7.2±1.3	5.0±0.7	5	9	8	2
对照组	27	12.8±4.6	10.7±2.5	10.7±3.2	7.5±3.5	25.6±3.4	22.3±4.7	6.8±1.3	5.8±1.1	3	7	10	7
统计值	0	t=0.165	t=3.972	t=0.192	t=2.521	t=0.416	t=2.273	t=1.441	t=2.774	χ²=4.694
P值	?	0.870	<0.001	0.849	0.015	0.679	0.028	0.173	0.008	0.030

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