To explore experiences and literatures of laparoscopic minimally invasive surgery for renal cell carcinoma with high post-hepatic inferior vena cava tumor thrombus.

Female patient, 61 years old, clinical diagnosis: right kidney cancer with high post-hepatic inferior vena cava tumor thrombus. Comprehensive evaluation of surgical risk before surgery, organization of multidisciplinary consultation for patients were performed detailed perioperative treatment and care plan, laparoscopic radical nephrectomy for right kidney cancer + high post-hepatic inferior vena cava tumor thrombectomy + retroperitoneal lymph node dissection. The operation was successfully completed. Postoperative care and close coordination were closely observed for the patient's condition changes.

The operation was successfully completed, operation time was 390 minutes, and there was no conversion to open surgery. During the operation, the right and left renal veins and the posterior inferior vena cava were directly connected to the distal end of the second hepatic hilum. The inferior vena cava in the proximal right renal vein was cut the vein wall, and the lower part of the tumor thrombus invaded the vein wall. Excision of part of the vena cava wall to completely remove the tumor thrombus, restore the left renal vein, vena cava blood flow back to the barrier. Postoperative pathological findings were consistent with clear cell carcinoma, cancer tissue invasion of renal sinus fat, and retroperitoneal lymph nodes(-). No tumor recurrence was seen after 6 months of follow-up.

Laparoscopic minimally invasive surgery for the treatment of renal cell carcinoma with high post-hepatic inferior vena cava tumor thrombus is safe and feasible. The multidisciplinary assisted model provides a new option for difficult and complicated cases, which is worthy of further clinical promotion.