To analyze the risk factors for hyperlactatemia in patients undergoing retroperitoneoscopic surgery.

The clinical data were collected from patients who underwent retroperitoneoscopic surgery in the First Hospital of Shanxi Medical University from January 1, 2018 to June 30, 2019. The patients were divided into high lactate group and normal lactate group according to the lactate value during the operation. To analyze the relevant data by univariate analysis and multivariate Logistic regression analysis.

Among 726 patients, 76(10.5%) cases lactate value increased. Univariate analysis showed that the liver Child-Pugh score, serum creatinine concentration, BMI, duration of operation and pneumoperitoneum, bladder pressure during the pneumoperitoneum, occurrence of prolonged hypotension and the cases of pheochromocytoma resection in the high lactate group were higher than those in the normal lactate group, the urine volume was lower, with statistically signficant differences (P<0.05). Multivariate Logistic regression analysis showed that the liver Child-Pugh score(OR=9.776, 95%CI 4.689-20.383, P<0.001), the serum creatinine concentration (OR=1.134, 95%CI 1.083-1.189, P<0.001), the duration of pneumoperitoneum (OR=1.021, 95%CI 1.001-1.042, P=0.043), pheochromocytoma resection (OR=5.146, 95%CI 1.229-21.543, P=0.025), prolonged hypotension (OR=12.956, 95%CI 2.028-82.753, P=0.007) were risk factors of hyperlactatemia for retroperitoneoscopic surgery.

The preoperetive liver Child-Pugh score, serum creatinine concentration, pneumoperitoneum duration, pheochromocytoma resection and prolonged hypotension are the independent risk factors of hyperlactatemia in retroperitoneoscopic surgery.