To explore the effects of transurethral plasmakinetic enucleation of the prostate (PKEP) and transurethral plasmakinetic resection of the prostate(PKRP) on sexual function in patients with benign prostatic hyperplasia (BPH).

The manuscript of Chinese and English were searched in PubMed, Cochrane Library, Springer link, Web of Science, CNKI, VIP, CBM and Wanfang database,which content about the effect of PKEP and PKRP on the sexual function of patients with BPH. The retrieval time was from the establishment of the database to May 1, 2020. The trial type was randomized controlled trial (RCT), and the references of the included literatures were manually searched. The screening, data extraction and quality evaluation were performed in strict accordance with the specified inclusion and exclusion criteria. Meta-analysis was performed using RevMan 5.3 statistical software.

After screening, 14 articles were included, 12 in Chinese and 2 in English. A total of 1 699 subjects were included. Meta-analysis showed that compared with PKRP, at 6 months after operation, PKEP had higher IIEF-5 score [SMD=0.53, 95%CI (0.11-0.95), P<0.05], less incidence of retrograde ejaculation [RR=0.75, 95% CI (0.65-0.86), P<0.05], and lower incidence of penile erectile dysfunction [RR=0.78, 95%CI (0.68-0.90), P<0.05]. However, there was no significant difference in IIEF-5 score, incidence of retrograde ejaculation and incidence of penile erectile dysfunction between the two surgical treatments at 12 months after operation (P>0.05).

Meta analysis shows that PKEP has higher IIEF-5 score, lower incidence of retrograde ejaculation and lower incidence of penile erectile dysfunction compared with PKRP at 6 months after operation.