To investigate the minimal invasive surgery for upper tract urothelial carcinoma(UTUC).

The data of 60 patients with UTUC who underwent two different surgical methods in our hospital from Sep. 2017 to Oct. 2021 were analyzed retrospectively. 30 cases (modified group) received complete transperitoneal laparoscopic nephroureterectomy with a single body position and distal ureter resection using a custom-made antislip laparoscopic bulldog clamp, while 30 cases (traditional group) was treated with radical retroperitoneal laparoscope nephroureterectomy plus open-surgery bladder sleeve resection combined with lower abdominal oblique incision. The perioperative data and follow-up results of the two groups were analyzed.

All surgeries of the two groups were successfully completed. The operation time, hemorrhage volume, the amount of postoperative drainage, drainage tube removal time and postoperative hospital stay in the modified group were all shorter than those in the traditional group, with statistical significance (P<0.05). There was no significant difference in the leaving time, the recovery time of postoperative gastrointestinal function, postoperative bladder tumor recurrence and follow-up time between the two groups (P>0.05). All patients were followed up for 1-48 months. A total of 8 cases of bladder tumor recurrence, including 2 cases in modified group and 6 cases in traditional group, were treated by transurethral resection of bladder tumor, and the rest were tumour-free.

Transperitoneal laparoscopic nephroureterectomy with a single body position and distal ureter resection using a custom-made laparoscopic bulldog clamp is more consistent with the principle of radical treatment of tumors. It is a safe, minimally invasive, feasible and effective method, which is suitable for promotion in clinical.