To evaluate the safety and efficacy of laparoscopic extraperitoneal radical cystectomy with orthotopic ileal neobladder.

A retrospective analysis was performed on 8 patients with bladder cancer who underwent laparoscopic extraperitoneal radical cystectomy with orthotopic ileal neobladder in The Second Affiliated Hospital of Anhui Medical University from March 2021 to February 2022. The basic data, operative data and postoperative follow-up data of the patients were collected.

All patients had successful operations. The average age of all patients was [65(40-78)] years, BMI was [23.85(19.59-29.0)] kg/m², operation time was [280.5(235.0-366.0)] min, intraoperative blood loss was [100(50-200)] ml, ventilation time was [3(2-4)] d, postoperative hospital stay was[11.5(10.0-20.0)] d, and the number of lymph nodes dissected was [13.5(8.0-29.0)]. Among them, one patient had poor incision healing and another had urine leakage. Six patients received preoperative neoadjuvant therapy, and 2 of them had postoperative pathology at T₀ stage. The median follow-up time was 11 months, including 1 case with bone metastasis, 1 case with urinary tract infection, and 1 case with hydronephrosis.

Laparoscopic extraperitoneal radical cystectomy with orthotopic ileal neobladder is safe and feasible. Because the peritoneal integrity is retained to a great extent and the interference of intestinal tract is avoided through peritoneal operation for a long time, it is beneficial to reduce intestinal complications and shorten the length of hospital stay, which is worthy of clinical promotion.