To investigate surgical methods of adrenal tumor and find a best way to preserve adrenal function.

The analysis was performed on 150 patients with adrenal tumor in Department of Urology of Jinling Hospital from January 2016 to July 2021, group A (100 patients) performed modified retroperitoneal laparoscopic surgeries, with no damage on adrenal artery and tissue. According to patients’ conditions, group A1 performed laparoscopic mechanical resection of superficial adrenal tumors, group A2 performed temporal blocking adrenal central vein and mechanical resection of adrenal tumor surgery in retroperitoneal laparoscopic surgery and group A3 performed priority blocking adrenal central vein and mechanical resection of adrenal tumor surgery in retroperitoneal laparoscopic surgery. Moreover, group B (50 patients) performed retroperitoneal laparoscopic tumor resection. These data was analyzed and evaluated to make conclusion.

The blood loss, operative time, postoperative drainage and follow-up time of group A were significantly better than retroperitoneal laparoscopic surgery. There were significant diffidence among these three modified surgeries in blood loss, operative time, and follow-up time (P<0.001), and the modified group did no need more long-term oral hormone therapy after surgery.

The modified surgical method can retain the adrenal artery to maintain the maximum normal adrenal tissue and their physiological function, meanwhile it also avoid electric coagulation and thermal damage to facilitate postoperative wound healing and early clinical rehabilitation. Especially, it was essential for patients with isolated adrenal gland and familial or hereditary diseases to avoid lifelong hormone replacement therapy.