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Chinese Journal of Endourology(Electronic Edition) ›› 2024, Vol. 18 ›› Issue (06): 547-552. doi: 10.3877/cma.j.issn.1674-3253.2024.06.003

Special Issue:

• Clinical Research • Previous Articles     Next Articles

Diagnosis and treatment of inflammatory myofibroblastic tumor of urinary bladder: report of four cases and literature review

Hua Wang1, Su'e Cao1, Jianjie Wu1, Jinming Di1,()   

  1. 1.Department of Urology,2Department of Radiology,the Third Affiliated Hospital,Sun Yat-sen University,Guangzhou 510630,China
  • Received:2024-06-06 Online:2024-12-01 Published:2024-11-26
  • Contact: Jinming Di

Abstract:

Objective

To investigate the clinical and imaging features of inflammatory myofibroblastic tumor of urinary bladder (IMTUB),aiming to improve the clinical diagnosis and treatment of this rare disease.

Methods

The clinic data of 4 cases IMTUB confirmed by pathology from December 2008 to July 2023 were retrospectively analyzed,and related literatures were reviewed.

Results

All cases were presented with severe urinary irritation while two of them complained gross hematuria. It can be described as clear submucosal border lesions grow in an expansive way and annular or delayed enhancement on contrast-enhanced CT. MRI showed slightly higher signal intensity on T2WI,enhancement of lesions was obvious after enhancement. Partial cystectomy was performed to completely remove the tumor in all cases.

Conclusions

IMTUB is a rare benign tumor with low malignant potential and is easily misdiagnosed as a malignant bladder tumor. It should be strongly suspect to IMTUB while the lesions on CT or MR appear to the following features,including the submucosal polyps grow in a nodular expansive way,annular enhancement sign or delayed contrast enhancement sign. In addition,routine biopsy of bladder tumors is necessary for this type of tumor to clarify the nature and avoid misdiagnosis. Partial cystectomy is a good choice to cure this disease which has a good prognosis.

Key words: Inflammatory myofibroblastic tumor of urinary bladder, Rare disease, Misdiagnose, Radiologic characteristics

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