Risk factors of urosepsis following flexible ureteroscopy with holmium laser

doi:10.3877/cma.j.issn.1674-3253.2018.01.005

Abstract

Abstract:

Objective

To evaluate the effectiveness of flexible ureteroscopy (FURS) for treating kidney stones and the risk factors of urosepsis following flexible ureteroscope with holmium laser.

Methods

The data of 66 patients with kidney stones who underwent flexible ureteroscopy with holmium laser at our hospital from January 2015 to September 2016, including gender, age, comorbidity, urine analysis results, urine culture results, blood test results, stone size, and operative duration were analyzed retrospectively. Patients with and without urosepsis were assigned to groups A and B, respectively. The dependent variables were postoperative urosepsis, and the risk factors for urosepsis following flexible ureteroscope were assessed using Chi-square tests and multivariate logistic regression analyses.

Results

All surgeries were successfully completed. The incidence of urosepsis after FURS was 13.6% (n=9). Univariate analyses of groups A and B indicated that pyuria, stonesize, operative duration, and infectious stones were significantly different between two groups (P<0.05). Multivariate logistic regression analyses indicated that pyuria (P=0.019), operative duration (P=0.021), and infectious stones (P=0.032) were independently related to urosepsis.

Conclusion

Pyuria, operative duration, and infectious stones were risk factors for urosepsis following flexible ureteroscopy.

Key words: Flexible ureteroscope, Kidney stones, Urosepsis, Risk factors

Zhenhua Zhao, Guoping Zhao, Dongsheng Zheng, Shijie Chen, Zhijian Shi, Dai Li, Yuhong Xin. Risk factors of urosepsis following flexible ureteroscopy with holmium laser[J]. Chinese Journal of Endourology(Electronic Edition), 2018, 12(01): 16-19.

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URL: https://zhqjmnmwkzz.cma-cmc.com.cn/EN/10.3877/cma.j.issn.1674-3253.2018.01.005

https://zhqjmnmwkzz.cma-cmc.com.cn/EN/Y2018/V12/I01/16

Figures/Tables 2

References 14

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自变量	组A	组B	P值
例数	9	57	?
年龄（岁，±s）	46±7	47±9	0.832
性别（男/女，例）	4/5	23/34	0.569
糖尿病史[例（%）]	2（22.22）	07（12.28）	0.355
高血压病史[例（%）]	1（11.11）	05（08.77）	0.601
肾功能不全[例（%）]	1（11.11）	07（12.28）	0.702
肾盂积水[例（%）]	4（44.44）	30（52.63）	0.46
结石手术史[例（%）]	3（33.33）	17（29.82）	0.554
术前尿培养阳性[例（%）]	3（33.33）	16（28.07）	0.511
脓尿[例（%）]	8（88.89）	20（35.09）	0.003
结石大小（cm，±s）	02.2±0.3	01.6±0.4	0.000
手术时间（min，±s）	96±18	57±14	0.000
感染结石[例（%）]	4（44.44）	07（12.28）	0.036

自变量	组A	组B	P值
例数	9	57	?
年龄（岁，±s）	46±7	47±9	0.832
性别（男/女，例）	4/5	23/34	0.569
糖尿病史[例（%）]	2（22.22）	07（12.28）	0.355
高血压病史[例（%）]	1（11.11）	05（08.77）	0.601
肾功能不全[例（%）]	1（11.11）	07（12.28）	0.702
肾盂积水[例（%）]	4（44.44）	30（52.63）	0.46
结石手术史[例（%）]	3（33.33）	17（29.82）	0.554
术前尿培养阳性[例（%）]	3（33.33）	16（28.07）	0.511
脓尿[例（%）]	8（88.89）	20（35.09）	0.003
结石大小（cm，±s）	02.2±0.3	01.6±0.4	0.000
手术时间（min，±s）	96±18	57±14	0.000
感染结石[例（%）]	4（44.44）	07（12.28）	0.036

变量	OR值（95%CI）	P值
年龄	0.775（0.336~1.794）	0.552
性别	1.016（0.988~1.044）	0.270
糖尿病史	1.074（0.233~4.956）	0.928
高血压病史	0.840（0.334~2.079）	0.693
结石手术史	1.159（0.336~3.986）	0.816
肾功能不全	4.404（0.989~19.632）	0.055
肾盂积水	0.565（0.155~2.066）	0.388
术前尿细菌培养	0.965（0.844~1.088）	0.486
结石大小	0.029（0.001~1.247）	0.065
脓尿	5.307（1.353~20.807）	0.019
手术持续时间	1.038（1.000~1.072）	0.021
感染结石	5.507（1.172~25.740）	0.032

变量	OR值（95%CI）	P值
年龄	0.775（0.336~1.794）	0.552
性别	1.016（0.988~1.044）	0.270
糖尿病史	1.074（0.233~4.956）	0.928
高血压病史	0.840（0.334~2.079）	0.693
结石手术史	1.159（0.336~3.986）	0.816
肾功能不全	4.404（0.989~19.632）	0.055
肾盂积水	0.565（0.155~2.066）	0.388
术前尿细菌培养	0.965（0.844~1.088）	0.486
结石大小	0.029（0.001~1.247）	0.065
脓尿	5.307（1.353~20.807）	0.019
手术持续时间	1.038（1.000~1.072）	0.021
感染结石	5.507（1.172~25.740）	0.032

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