To explored the values of enhanced recovery after surgery (ERAS) based on multimodal anesthesia in laparoscopic radical cystectomy.

The data of patients undergoing laparoscopic radical cystectomy with or without ilealneobladder during perioperative period were collected from January 2015 to December 2017 in our hospital, 9 patients in Group ERAS who were managed with ERAS protocols based on multimodal anesthesia preoperatively, and 27 in Group control who were managed with routine protocols preoperatively. Length of hospital stay, pain after surgery and other parameters were compared between the two groups.

Compared with Group control, length of stay and postoperative length of stay were significantly shorter (20 d vs 33 d, P=0.002; 9 d vs 18 d, P=0.002), intra-operative fluid volume was significantly less [5.5 (ml/kg/h) vs 8.1 (ml/kg/h), P=0.003], a higher proportion of patients receiving analgesics on time postoperatively (P=0.001), a lower proportion of those requiring extra analgesics (P=0.046), and the first postoperative defecation was significantly faster (P=0.035, in Group ERAS). There was no significant difference between the two groups in the total cost, anesthesia costs and postoperative complications.

The use of multimodal anesthesia combined with enhanced recovery in laparoscopic radical cystectomy can speed up the recovery of patients and reduce the need for extra analgesics, and there was no significant difference in postoperative complications.