原发性肾滑膜肉瘤一例报告并文献复习

doi:10.3877/cma.j.issn.1674-3253.2020.06.017

中华腔镜泌尿外科杂志(电子版) ›› 2020, Vol. 14 ›› Issue (06) : 473 -476. doi: 10.3877/cma.j.issn.1674-3253.2020.06.017

所属专题：经典病例；经典病例；文献；

病例研究

原发性肾滑膜肉瘤一例报告并文献复习

赖义明¹, 李璐杰², 夏坤¹, 黄国辉³, 彭圣萌¹, 吴宛桦¹, 范辉阳¹, 雷震¹, 郭正辉¹^,^†(

)

^1. 510120　广州，中山大学孙逸仙纪念医院泌尿外科
^2. 510080　广州，中山大学中山医学院临床医学系
^3. 510120　广州，中山大学孙逸仙纪念医院病理科

收稿日期:2020-05-14 出版日期:2020-12-01
通信作者: 郭正辉
基金资助:
国家自然科学基金面上项目(81272807，81772733，81972384); 国家自然科学基金青年项目(81802527); 广东省省级科技计划项目(2014A020212018，2016A020215011); 广州市科技计划项目(201605130835264); 广东省医学科研基金(A2015113)

Primary renal synovial sarcoma: a case report and literature review

Yiming Lai¹, Lujie Li², Kun Xia¹, Guohui Huang³, Shengmeng Peng¹, Wanhua Wu¹, Huiyang Fan¹, Zhen Lei¹, Zhenghui Guo¹^,^†()

^1. Department of Urology, Sun Yat-Sen Memorial Hospital, Sun Yat-Sen University, Guangzhou 510120, China
^2. Department of Clinical Medicine, Zhongshan School of Medicine, Sun Yat-Sen University, Guangzhou 510080, China
^3. Department of Pathology, Sun Yat-Sen Memorial Hospital, Sun Yat-Sen University, Guangzhou 510120, China

Received:2020-05-14 Published:2020-12-01
Corresponding author: Zhenghui Guo
About author:
Corresponding author: Guo Zhenghui, Email: guozhhui@mail.sysu.edu.cn

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引用本文：

赖义明, 李璐杰, 夏坤, 黄国辉, 彭圣萌, 吴宛桦, 范辉阳, 雷震, 郭正辉. 原发性肾滑膜肉瘤一例报告并文献复习[J]. 中华腔镜泌尿外科杂志(电子版), 2020, 14(06): 473-476.

Yiming Lai, Lujie Li, Kun Xia, Guohui Huang, Shengmeng Peng, Wanhua Wu, Huiyang Fan, Zhen Lei, Zhenghui Guo. Primary renal synovial sarcoma: a case report and literature review[J]. Chinese Journal of Endourology(Electronic Edition), 2020, 14(06): 473-476.

目的

探讨原发性肾滑膜肉瘤的临床特点及诊治方法。

方法

回顾性分析我院原发性肾滑膜肉瘤1例的临床资料，并对国内外相关文献进行回顾。

结果

患者接受根治性左肾切除术，术后病理回报为原发性肾滑膜肉瘤。

结论

原发性肾滑膜肉瘤非常罕见，无特异性临床特点及影像表现，诊断主要依靠病理及免疫组化，SYT-SSX融合基因有提示作用，主要治疗方案为手术，化疗对生存率的影响还需进一步研究。

关键词: 肾肿瘤, 滑膜肉瘤, 文献复习

Objective

To discuss the clinical features and treatment of primary renal synovial sarcoma(PRSS).

Methods

The data of a rare case of PRSS were analyzed retrospectively, a comprehensive review of the literature was presented.

Result

The patient was treated by left radial nephrectomy. The result of pathology indicated PRSS.

Conclusions

There was no typical clinical manifestation or imaging feature of PRSS. We depended pathology and immunohistochemical examination to diagnosis PRSS, and SYT-SSX fusion gene was also useful. We proposed multimodality treatment measures including surgery and anthracycline-based chemotherapy.

Key words: Kidney Neoplasms, Synovial Sarcoma, Literature Review

图1 原发性肾滑膜肉瘤患者术前CT检查结果

图2 原发性肾滑膜肉瘤患者术后病理检查结果

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