To compare efficacy and safety of transurethral plasmakinetic resection of prostate (PKRP) and transurethral resection of prostate (TURP) for the treatment of benign prostatic hyperplasia(BPH), to provide the basis for the clinical treatment of BPH.

Eighty four patients with BPH were enrolled in PKRP group (n=42) and TURP group (n=42). The differences of operation index and quality of life score (QOL), maximum urinary flow rate (Qmax), residual urine volume (RUV) and the international prostate symptom score (IPSS) between the two group were compared.

Average operation time, average bleeding volume and indwelling catheter time were shorter and lower in PKRP group, the differences were statistically significant (P<0.05), but there was no significant difference in the washing time and postoperative hospitalization time between the two groups (P>0.05). Compared with preoperative, QOL, Qmax, RUV, IPSS and other indicators were improved postoperatively (P<0.01), but there was no significant difference between the two group (P>0.05). The incidence of complications in PKRP group was lower than TURP group (χ²=4.46, P<0.05).

The clinical efficacy and safety of PKRP was better than TURP, and the incidence of complications was lower, it was an ideal operation for BPH which was worthy of clinical application and promotion.