To evaluate the surgical techniques and clinical efficacy of laparoscopic resection combined with aspiration for central renal angiomyolipoma.

The clinical data of one case with giant central renal angiomyolipoma who underwent laparoscopic resection and aspiration in our hospital in November 2015 were analyzed and relevant literatures were reviewed.

The case successfully underwent retroperitoneal laparoscopic resection of right renal angiomyolipoma. Operative time was 200 min, warm ischemia time was 45 min, the blood loss was 1 200 ml and intraoperative transfusion was 600 ml. Postoperative pathology confirmed the diagnosis of right renal angiomyolipoma. Postoperative hospital stay was 6 days, ambulation time was 5 days. Followed up for9 months with normal renal function and no tumor metastasize or recurrence.

Laparoscopic resection and aspiration for complex renal angiomyolipoma is a feasible, safe and effective minimally invasive procedure. But for giant renal agiomyolipoma, large wound and bleeding occur after aspiration related complications and oncological outcomes that need further study.