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Chinese Journal of Endourology(Electronic Edition) ›› 2022, Vol. 16 ›› Issue (02): 177-180. doi: 10.3877/cma.j.issn.1674-3253.2022.02.018

• Cases Researches • Previous Articles     Next Articles

Diagnosis and treatment of prostate cancer with rectal cancer symptoms and literatures review

Jiayu Huang1, Qiang Huang1, Dejuan Wang1, Bo Ma1, Hu Qu1, Bing Yao1, Wenwen Zhong1, Lei Ye1, Qiang Guo1, Lei Wang1, Jianjian Wu1, Jianguang Qiu1, Zhongyang Wang1,()   

  1. 1. Department of Urology, the Sixth Affiliated Hospital, Sun Yet-sen University, Guangzhou 510630, China
  • Received:2021-01-20 Online:2022-04-01 Published:2022-04-28
  • Contact: Zhongyang Wang

Abstract:

Objective

To investigate the diagnosis and treatment of prostate cancer with rectal cancer symptoms.

Methods

The data of 3 cases of prostate cancer with rectal cancer symptoms in our hospital were analyzed retrospectively.

Results

All 3 patients were admitted to the gastrointestinal department of our hospital due to gastrointestinal symptoms. Patient 2: digital rectal examination showed no abnormality, digital rectal examination was able to touch the mass in both patients 1 and 3. Both CT and MRI showed masses involving the prostate and rectum,colonoscopy showed a circumferential mass with a narrow lumen,the histology is high/low differentiated adenocarcinoma,all patients were initially diagnosed with rectal cancer.The patient 1 serum PSA:2.532 ng/ml, Miles surgery was performed, Gleason: 5+4=9 after surgery, immunohistochemistry: PSA/P504s (+), finally diagnosed as prostate cancer, and postoperative endocrine therapy was added.After urological consultation, serum PSA of patient 2 and patient 3 were >100 ng/ml and 153.49 ng/ml, Gleason scores were 5+3=8 and 4+3=7, respectively, and immunohistochemical PSA/P504s were (+). Finally, prostate cancer was diagnosed, and endocrine therapy and total pelvic organ resection were used for treatment.

Conclusion

The diagnosis of prostate cancer should be combined with medical history, various examinations, histology and immunohistochemistry, and avoided wrong treatment.

Key words: Rectal cancer, Prostate cancer, Misdiagnosis, Metastasis

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