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Chinese Journal of Endourology(Electronic Edition) ›› 2022, Vol. 16 ›› Issue (05): 400-403. doi: 10.3877/cma.j.issn.1674-3253.2022.05.004

• Clinical Research • Previous Articles     Next Articles

Clinical analysis of urinary complications of brachytherapy in patients of prostate cancer

Jiahui Zhao1,(), Zhu Hou1, Yong Luo1, Mingchuan Li1, Tao Peng1, Yongxing Wang1, Yongguang Jiang1   

  1. 1. Department of Urology, Beijing Anzhen Hospital, Capital Medical University, Beijing 100029, China
  • Received:2021-07-06 Online:2022-10-01 Published:2022-09-29
  • Contact: Jiahui Zhao

Abstract:

Objective

To analyze the side effects and complications in prostate cancer patients treated with brachytherapy.

Methods

A total of 120 prostate cancer patients with average age of (73±5) years were recruited. All the patients were diagnosed as prostate cancer and accepted prostate brachytherapy from 2011 to 2019 under the guidance of transrectal ultrasound. The adverse reactions of urinary tract and their complications after prostate cancer 125I seed implantation were analyzed retrospectively.

Results

A total of 120 patients with prostate cancer were collected and the clinical average Gleason score was (8.4±1.1). The IPSS scores of the patients were (13.1±3.6), (21.6±4.6), (19.2±4.4), (15.9±3.9), (13.9±3.1) and (13.5±2.7) before operation, 1 month after operation, 3 months after operation, half a year after operation, 1 year after operation and 2 years after operation, respectively. The incidence of grade I and grade II complications was 14.2% and 5.8% respectively within 1 month after operation, and 5.0% and 2.5% respectively within 3 months after operation. There were no grade III or IV complications.

Conclusions

Prostate brachytherapy is a minimally invasive treatment for prostate cancer. Although the implantation of particles has a certain impact on the urination of patients, but the degree is relatively light, with a certain degree of self-limiting. Intraoperative accurate localization and making accurate implantation plan are factors to the prevention of serious complications.

Key words: Brachytherapy, Prostate cancer, Complication

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