To investigate the clinical manifestations and imaging features of paraganglioma of the urinary bladder (PUB).

The clinical manifestations, pathological and imaging features of five patients with pathologically proved PUB were analyzed retrospectively between Dec. 2012 to Jul. 2020 in our hospital, and related literatures were reviewed.

Only 1 patient of the five presented with dysuria, urinary frequency and urgency, the other 4 cases were found by chance in physical examination. All the 5 lesions presented as solid mass on CT or MRI imaging features,1 was intramural, oval shape with smooth surface, 4 were submucosal, irregular shape with uneven surface. All lesions had homogeneous density without cystic, necrosis or calcification. MRI showed slightly higher signal intensity on both T1WI and T2WI, focal enhancement was obvious. Submucosal lesions were indistinct with the adjacent bladder wall, and local bladder wall was thickened and enhanced.

PUB is a rare type of benign lesions, those asymptomatic PUB were often misdiagnosed as malignant neoplasm pre-operatively. Familiarity with the imaging features, combined with typical clinical manifestations, bladder paraganglioma should be considered as a differential diagnosis to neoplasm before operation, which is helpful for the urologists to make correct surgical methods and avoid complications during operation.