Correlation between ultrasonic parameters and renal function in children with hydronephrosis caused by ureteropelvic junction obstruction

doi:10.3877/cma.j.issn.1674-3253.2023.04.012

Abstract

Abstract:

Objective

To analyze the correlation between ultrasonic parameters and renal function in children with hydronephrosis caused by ureteropelvic junction obstruction (UPJO).

Methods

92 children (disease group) with hydronephrosis caused by UPJO treated in Xuzhou Children's Hospital from February 2020 to April 2021 and 92 healthy children (control group) were selected. The renal interlobar artery resistance index (RI), systolic maximum blood flow velocity (V_max) and diastolic minimum blood flow velocity (V_min) were measured by color Doppler ultrasound, and the arterial resistance index ratio (RIR) was calculated, glomerular filtration rate (GFR) was measured by renal radionuclide dynamic imaging, and the contents of blood urea nitrogen (BUN) and serum creatinine (SCr) were detected by enzyme method. Ultrasound parameters (RI, V_max, V_min, RIR) and renal function indexes (GFR, bun, SCR) were compared between the disease group and control group, and Pearson method was used to analyze the correlation between ultrasound parameters and renal function indexes in the disease group.

Results

V_max, V_min and GFR of kidney in the disease group were lower than those in the control group (P<0.05), and RI, RIR, BUN and SCr were higher than those in the control group (P<0.05). RI and RIR were negatively correlated with GFR (P<0.05), positively correlated with BUN and SCr (P<0.05). V_max and V_min were positively correlated with GFR (P<0.05), negatively correlated with BUN and SCr (P<0.05).

Conclusions

Compared with healthy children, RI, RIR increased, and V_max, V_min decreased in children with hydronephrosis caused by UPJO. The ultrasound parameters are correlated with renal function.

Key words: Ultrasonic parameters, Ureteropelvic junction obstruction, Hydronephrosis, Children, Renal function

Jinghan Zhao, Yulong Chen, Chen Zhang. Correlation between ultrasonic parameters and renal function in children with hydronephrosis caused by ureteropelvic junction obstruction[J]. Chinese Journal of Endourology(Electronic Edition), 2023, 17(04): 372-376.

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References 22

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组别	例数	RI	V_max（ml/min）	V_min（ml/min）	RIR	GFR（ml/min）	BUN（mg/dl）	SCr（mg/dl）
疾病组	92	0.79±0.11	75.2±12.5	15.5±2.5	1.06±0.14	4.9±0.7	8.1±1.4	125±19
对照组	92	0.56±0.06	93.1±16.1	28.0±4.9	0.79±0.08	7.9±1.2	4.9±0.7	072±13
t值		10.058	6.174	16.047	11.721	14.841	13.981	16.277
P值		<0.001	<0.001	<0.001	<0.001	<0.001	<0.001	<0.001

组别	例数	RI	V_max（ml/min）	V_min（ml/min）	RIR	GFR（ml/min）	BUN（mg/dl）	SCr（mg/dl）
疾病组	92	0.79±0.11	75.2±12.5	15.5±2.5	1.06±0.14	4.9±0.7	8.1±1.4	125±19
对照组	92	0.56±0.06	93.1±16.1	28.0±4.9	0.79±0.08	7.9±1.2	4.9±0.7	072±13
t值		10.058	6.174	16.047	11.721	14.841	13.981	16.277
P值		<0.001	<0.001	<0.001	<0.001	<0.001	<0.001	<0.001

肾脏超声参数	肾小球滤过率		血尿素氮		血肌酐
肾脏超声参数	r值	P值	r值	P值	r值	P值
肾叶间动脉阻力指数	-0.706	0.032	-0.712	0.038	-0.741	0.026
肾叶间动脉收缩期最大血流速度	-0.731	0.046	-0.752	0.042	-0.733	0.028
肾叶间动脉舒张期最小血流速度	-0.701	0.041	-0.741	0.035	-0.738	0.043
肾叶间动脉阻力指数比率	-0.702	0.028	-0.716	0.037	-0.742	0.026

肾脏超声参数	肾小球滤过率		血尿素氮		血肌酐
肾脏超声参数	r值	P值	r值	P值	r值	P值
肾叶间动脉阻力指数	-0.706	0.032	-0.712	0.038	-0.741	0.026
肾叶间动脉收缩期最大血流速度	-0.731	0.046	-0.752	0.042	-0.733	0.028
肾叶间动脉舒张期最小血流速度	-0.701	0.041	-0.741	0.035	-0.738	0.043
肾叶间动脉阻力指数比率	-0.702	0.028	-0.716	0.037	-0.742	0.026

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