Research progress of cell death in renal ischemia-reperfusion injury

doi:10.3877/cma.j.issn.1674-3253.2025.05.017

Abstract

Abstract:

Renal ischemia-reperfusion is one of the main causes of acute kidney injury, however, the underlying mechanisms are not yet clear. With the continuous deepening of research, it has been found that cell death attracted increasing attention in renal ischemia-reperfusion injury, including cell apoptosis, cell pyroptosis, cell autophagy, ferroptosis, etc. This article reviews the mechanisms of various cell deaths in renal injury, providing new directions for the prevention and treatment of renal ischemia-reperfusion injury.

Key words: Renal, Ischemia-reperfusion injury, Apoptosis, Autophagy, Pyroptosis, Ferroptosis

Jieyan Wang, Bowen Hu, Hui Liang. Research progress of cell death in renal ischemia-reperfusion injury[J]. Chinese Journal of Endourology(Electronic Edition), 2025, 19(05): 653-657.

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