Bacteriological profile of urinary tract abnormalities children with urinary tract infection

doi:10.3877/cma.j.issn.1674-3253.2018.04.003

Abstract

Abstract:

Objective

To investigate the clinical characteristics, pathogens and drug resistance in urinary tract abnormalities children with urinary tract infection.

Methods

In a retrospective and observational study between January 2012 and December 2016, children with urinary tract infection were recruitment. Based on radiographic test, patients were divided into the normal urinary tract group and the abnormal urinary tract group.

Results

Four hundred and seventy six cases were included, and 162 were identified with urinary tract abnormalities, of which the most common diagnosis (43.83%) was hydronephrosis. Male children with urinary tract abnormalities were subjected to recurrent urinary tract infection (UTI). Fever was the most common clinical presentation. A total of 166 strains of pathogenic bacteria were detected, and gram-negative bacteria were ranking the first (71.08%). E. coli and Enterococcus were responsible for 40.36% and 22.89% children with UTI, respectively. However, enterococcus faecalis were more frequently detected in children with urinary tract abnormalities. There were no significant difference in bacteria resistance to common use antibiotics between the two groups.

Conclusion

Male children with urinary tract abnormalities were the risk factor for UTI, especially infection with enterococcus.

Key words: Urinary tract infection, Urinary tract abnormalities, Pathogens, drug resistance

Chujun Huang, Dejuan Wang, Lifen Yang, Jianfei Zhang, Jiazhou Lin, Mingxiang Ling, Zhuanggui Chen. Bacteriological profile of urinary tract abnormalities children with urinary tract infection[J]. Chinese Journal of Endourology(Electronic Edition), 2018, 12(04): 224-227.

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References 20

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项目	例数	构成比（%）
肾积水	71	43.83
肾脏弥漫性病变、肿胀	9	5.56
肾脏缩小，萎缩	4	2.47
单侧肾、一侧肾脏发育不良	3	1.85
肾脏囊性病变	3	1.85
重复肾	2	1.23
输尿管扩张	44	27.16
输尿管膀胱开口处狭窄	4	2.47
肾盂输尿管连接处狭窄	23	14.20
输尿管狭窄	9	5.56
输尿管异位开口、出口狭窄或闭锁	4	2.47
重复输尿管	3	1.85
膀胱输尿管反流	3	1.85
巨输尿管	4	2.47
膀胱壁增厚	15	9.26
下尿路异常（含外伤）	15	9.26
结石	23	14.20
肿瘤	8	4.94

项目	例数	构成比（%）
肾积水	71	43.83
肾脏弥漫性病变、肿胀	9	5.56
肾脏缩小，萎缩	4	2.47
单侧肾、一侧肾脏发育不良	3	1.85
肾脏囊性病变	3	1.85
重复肾	2	1.23
输尿管扩张	44	27.16
输尿管膀胱开口处狭窄	4	2.47
肾盂输尿管连接处狭窄	23	14.20
输尿管狭窄	9	5.56
输尿管异位开口、出口狭窄或闭锁	4	2.47
重复输尿管	3	1.85
膀胱输尿管反流	3	1.85
巨输尿管	4	2.47
膀胱壁增厚	15	9.26
下尿路异常（含外伤）	15	9.26
结石	23	14.20
肿瘤	8	4.94

项目		尿路正常组	尿路异常组	χ²值	P值
例数		314	162
性别
	男	170	119	16.718	<0.001 0
	女	144	43	16.718	<0.001 0
年龄
	0~1岁	131	72	01.993	0.741
	1~3岁	38	20
	3~7岁	59	34
	7~14岁	42	20
	14~18岁	44	16
发热		221	114	0	1.000
寒战		67	47	03.456	0.063
纳差、易激惹		58	35	00.668	0.414
尿路刺激症状		80	44	00.157	0.692
尿色浑浊		39	47	19.874	<0.0010
呕吐、腹泻		26	12	00.111	0.739
肉眼血尿		24	17	01.103	0.294
腰痛、腹痛		18	29	17.782	<0.0010
复发		52	90	77.631	<0.0010

项目		尿路正常组	尿路异常组	χ²值	P值
例数		314	162
性别
	男	170	119	16.718	<0.001 0
	女	144	43	16.718	<0.001 0
年龄
	0~1岁	131	72	01.993	0.741
	1~3岁	38	20
	3~7岁	59	34
	7~14岁	42	20
	14~18岁	44	16
发热		221	114	0	1.000
寒战		67	47	03.456	0.063
纳差、易激惹		58	35	00.668	0.414
尿路刺激症状		80	44	00.157	0.692
尿色浑浊		39	47	19.874	<0.0010
呕吐、腹泻		26	12	00.111	0.739
肉眼血尿		24	17	01.103	0.294
腰痛、腹痛		18	29	17.782	<0.0010
复发		52	90	77.631	<0.0010

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