To explore the diagnostic efficacy of three-dimensional MRI GRE sequence (3D-LAVA) gas-screen examination and fast recovery fast spin echo sequence (FRFSE) in early prostate cancer by magnetic resonance imaging (MRI).

The clinical data of 210 suspected cases of early prostate cancer in our hospital from June 2013 to June 2019 were reviewed. MRI 3D-LAVA and FRFSE sequence scanning were performed in all cases. The results of two scanning sequences were summarized and the efficacy of different methods in the diagnosis of early prostate cancer was analyzed. In addition, the diagnosis results of multi-parameter magnetic resonance imaging (mpMRI) were compared, and the receiver operating characteristic curve (ROC) was drawn to evaluate the efficacy of different methods in the diagnosis of early prostate cancer.

The ratio of early prostate cancer was 38.10%. The peak value and enhancement rate of early prostate cancer (+) patients were higher than those of prostate cancer (-) patients, and the peak time of early prostate cancer (+) patients was shorter than that of the latter, and the enhancement extent was smaller than that of the latter, the difference was statistically significant (P<0.05). The sensitivity of MRI 3D-LAVA dynamic enhancement combined with FRFSE sequence in the diagnosis of early prostate cancer was similar of MRI 3D-LAVA dynamic enhancement and FRFSE sequence alone, and the specificity, accuracy and AUC were higher than those of single diagnosis. The sensitivity, specificity and accuracy of 3D-LAVA dynamic contrast-enhanced MRI combined with FRFSE sequence in the diagnosis of early prostate cancer were comparable of mpMRI, and there was no significant difference in AUC between the two groups (P>0.05).

In the diagnosis of early prostate cancer, the efficiency of combination of 3D-LAVA dynamic enhancement and FRFSE sequence scanning is effective, which is in good agreement with pathological results, and is similar of mpMRI in the diagnosis of early prostate cancer.