To evaluate the efficacy and safety of retroperitoneoscopic partial nephrectomy for patients with reninoma and to improve the diagnosis and treatment of reninoma.

The records of 3 patients (2 males and 1 female) who underwent retroperitoneal laparoscopic partial nephrectomy at our center for treatment of reninoma between January 2012 and January 2020 were analyzed retrospectively. The median patient age was 18 years. The main clinical manifestations were hypertension and hypokalemia.The radiological images showed renal mass.

All procedures were successfully completed without conversion to open surgery. All patients did not receive blood transfusion, and there was no major complication intraoperatively or postoperatively. After surgery, the patients remained normotensive without any medication. Histopathologic examination confirmed the diagnosis of reninoma. All patients were followed up for a period of 1 to 4 years. The patients’s blood pressure remained normal and no local recurrences occurred.

Reninoma is a rare benign renal tumor. Because of the typical clinical and radiological findings, a correct preoperative diagnosis is possible in most cases. Laparoscopic partial nephrectomy is a safe, effective, and minimally invasive approach for the management of reninoma.