To compare the effects of transurethral unipolar ball electrode and plasmakinetic enucleation of prostate (TUPKEP) in the treatment of benign prostatic hyperplasia (BPH).

Sixty BPH patients who presented to the Department of Urology, Yantian District People's Hospital from March 2019 to January 2021, and required surgical treatment were divided into two groups by segmented randomization, 30 cases in each group. One group underwent transurethral monopolar ball electrode prostate enucleation and the other group underwent TUPKEP. Intraoperative blood loss, operation time, resected tissue weight, postoperative bladder irrigation time, indwelling catheter time, hospital stay, and main complications were compared between the two groups. After a follow-up of 6 months, the maximum urinary flow rate (Q_max), residual urine volume (RUV), International Prostate Symptom Score (IPSS) and quality of life (QOL) were compared between the two groups.

The operation was successful in both groups, and the 6-month follow-up was completed. There was statistical difference in intraoperative blood loss between ball enucleation group and plasma enucleation group (P<0.05). There was no statistical difference in tissue enucleation volume, operation time, postoperative bladder irrigation time, urinary catheter indwelling time and average hospital stay (P>0.05). No serious complications such as TURS and capsule perforation occurred in the two groups.

Transurethral enucleation of prostate with monopolar ball electrode is effective and worthy of further promotion at the primary hospitals with electrocision equipment.