To compare the safety and efficacy of 1 470 nm diode laser "mean trichotomy " enucleation of the prostate (Mt-DiLEP) and transurethral plasmakinetic enucleation (PKEP) in the treatment of benign prostatic hyperplasia (BPH).

195 patients with BPH were divided into two groups according to different surgical methods. 109 patients treated with Mt-DiLEP were divided into Mt-DiLEP group and 86 patients treated with PKEP were divided into PKEP group. Preoperative general data, perioperative indexes, intraoperative and postoperative complications and efficacy indexes of 2 groups were recorded and analyzed retrospectively.

The operation time of the Mt-DiLEP group was similar to that of the PKEP group, and the Mt-DiLEP group was superior to the PKEP group in terms of postoperative hospital stay, decreased value of hemoglobin and catheter indwelling time, with statistical differences between the two groups (all P<0.05). The postoperative Q_max, IPSS and QOL of the two groups 3 months after surgery were significantly improved than before, and there was no statistical significance in the postoperative Q_max, IPSS and QOL of the two groups (P>0.05). Complications such as intraoperative bleeding, postoperative urethral stricture and bleeding in the Mt-DiLEP group were less than those in the PKEP group (P<0.05).

Mt-DiLEP and PKEP have similar operation time and clinical efficacy in the treatment of BPH. However, Mt-DiLEP has the advantages of high surgical safety, less postoperative complications, shorter average hospital stay, which is a safe and effective surgical treatment of BPH, and it is worthy of clinical application.