Application value of DISCO imaging in differential diagnosis of benign prostatic hyperplasia and prostate cancer

doi:10.3877/cma.j.issn.1674-3253.2023.04.004

Abstract

Abstract:

Objective

To explore the application value of differential subsampling with cartesian ordering (DISCO) imaging technique in the differential diagnosis of prostate cancer (PCa) and benign prostatic hyperplasia (BPH).

Methods

The clinical data of 100 patients with prostatic diseases treated in Lingnan Hospital of the Third Affiliated Hospital of Sun Yat-sen University from January 2020 to December 2021 were collected. All patients underwent MRI examination, which was confirmed by biopsy pathology or surgical pathology, including 40 patients with PCa and 60 patients with BPH, MRI combined with DISCO imaging technology was used to measure the hemodynamic parameters, such as K^trans, Ve, IAUGC, MaxSlope and CER. The diagnostic value of each parameter was evaluated by ROC curve.

Results

Compared with BPH group, K^trans, CER, IAUGC, MaxSlope and Ve in PCa group were significantly higher (P<0.05). The areas under the ROC curve of K^trans, CER, IAUGC, Ve and MaxSlope in the diagnosis of PCa were 0.646, 0.697, 0.713, 0.613 and 0.669, respectively.

Conclusion

DISCO imaging technology can provide important reference value for the differential diagnosis of BPH and PCa.

Key words: DISCO, Denign prostatic hyperplasia, Prostate cancer, Differential diagnosis

Quanxi Li, Huijun Tang, Youjie Tang, Fei Yang. Application value of DISCO imaging in differential diagnosis of benign prostatic hyperplasia and prostate cancer[J]. Chinese Journal of Endourology(Electronic Edition), 2023, 17(04): 332-335.

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References 14

[1]	Fidler MM, Bray F, Soerjomataram I. The global cancer burden and human development: a review[J]. Scand J Public Health, 2018, 46(1): 27-36.
[2]	Tyson MD, Penson DF, Resnick MJ. The comparative oncologic effectiveness of available management strategies for clinically localized prostate cancer[J]. Urol Oncol, 2017, 35(2): 51-58.
[3]	Catala V, Vilanova JC, Gaya JM, et al. Multiparametric magnetic resonance imaging and prostate cancer: what's new[J]. Radiologia, 2017, 59(3): 196-208.
[4]	Barbieri S, Bronnimann M, Boxler S, et al. Differentiation of prostate cancer lesions with high and with low Gleason score by diffusion-weighted MRI[J]. Eur Radiol, 2017, 27(4): 1547-1555.
[5]	张可, 蒋伟, 黎卓君, 等．尿液前列腺癌基因（PCA3）联合多参数磁共振对前列腺癌的诊断价值[J/OL]．中华腔镜泌尿外科杂志(电子版), 2021, 15(6): 463-466.
[6]	Sprinkart AM, Marx C, Traber F, et al. Evaluation of exponential ADC (eADC) and computed DWI (cDWI) for the detection of prostate cancer[J]. Rofo, 2018, 190(8): 758-66.
[7]	Pettersson A, Robinson D, Garmo H, et al. Age at diagnosis and prostate cancer treatment and prognosis: a population-based cohort study[J]. Ann Oncol, 2018, 29(2):377-385.
[8]	Prashanth R. Epidemiology of prostate cancer[J]. World J Oncol, 2019, 10(2): 63-89.
[9]	Luo M, Zhang L, Jiang XH, et al. Intravoxel incoherent motion: application in differentiation of hepatocellular carcinoma and focal nodular hyperplasia[J]. Diagn Interv Radiol, 2017, 23(4): 263-271.
[10]	徐曦,张冬,黄家喜,等.体素内不相干运动成像及动态增强MRI在前列腺癌诊断及分级中的应用[J].中国医学影像学杂志, 2018, 26(10): 772-776, 780.
[11]	袁元, 魏毅,宋彬, 等. 钆塞酸二钠肝脏MRI多动脉期增强扫描评价肝血管解剖与CTA的对照研究[J].中华放射学杂志, 2019(12): 1086-1090.
[12]	袁为标, 陆大军, 高辉.等基于磁共振表观扩散系数图像的影像组学模型对鉴别前列腺癌和前列腺增生的价值[J/OL].中华腔镜泌尿外科杂志(电子版), 2022, 16(1): 14-18.
[13]	邱英良,郑晓林,邹玉坚,等.前列腺中央带前列腺癌与前列腺增生MRI弥散加权成像的多b值分析[J]. 中国CT和MRI杂志, 2018, 16(6):85-88, 92.
[14]	王立鹏,阳青松,张威,等.多参数磁共振成像在前列腺癌中的诊断价值[J].第二军医大学学报, 2019, 40(11): 1236-1241.

组别	例数	K^trans/(min^-1)	CER	IAUGC	Ve	MaxSlope
BPH	60	0.831±0.04	0.808±0.07	0.797±0.09	0.82±0.05	0.801±0.04
PCa	40	0.883±0.03	0.848 ±0.04	0.861±0.06	0.854±0.04	0.847±0.03
t值		3.630	4.212	4.579	2.909	3.781
P值		<0.001	<0.001	<0.001	0.004	<0.001

组别	例数	K^trans/(min^-1)	CER	IAUGC	Ve	MaxSlope
BPH	60	0.831±0.04	0.808±0.07	0.797±0.09	0.82±0.05	0.801±0.04
PCa	40	0.883±0.03	0.848 ±0.04	0.861±0.06	0.854±0.04	0.847±0.03
t值		3.630	4.212	4.579	2.909	3.781
P值		<0.001	<0.001	<0.001	0.004	<0.001

DISCO成像参数	AUC	95%CI	P值
K^trans /( min^-1)	0.646	0.546~0.747	0.009
CER	0.697	0.602~0.793	<0.0010
IAUGC	0.713	0.618~0.807	<0.0010
Ve	0.613	0.509~0.718	0.042
MaxSlope	0.669	0.57~0.768	0.003

DISCO成像参数	AUC	95%CI	P值
K^trans /( min^-1)	0.646	0.546~0.747	0.009
CER	0.697	0.602~0.793	<0.0010
IAUGC	0.713	0.618~0.807	<0.0010
Ve	0.613	0.509~0.718	0.042
MaxSlope	0.669	0.57~0.768	0.003

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[6]	Shuoru Liu, Gongwei Wang, Bin Zhang, Shuhao Li, Cheng Hu. Oncolytic virus M1 activates endoplasmic reticulum stress pathway to induce apoptosis of prostate cancer cells [J]. Chinese Journal of Endourology(Electronic Edition), 2023, 17(04): 388-393.
[7]	Bangyu Wang, Xiaopeng Chen, Guojun Tang, Jiani Wang. A preliminary study of the diagnostic value of urine extracellular vesicle circRNA classifier for prostate cancer [J]. Chinese Journal of Endourology(Electronic Edition), 2023, 17(04): 339-342.
[8]	Jingjun Mu, Zengni Ma, Xiaoming Cao. Analysis of risk factors for extraprostatic extension in clinically localized prostate cancer [J]. Chinese Journal of Endourology(Electronic Edition), 2023, 17(04): 326-331.
[9]	Xingli Shan, Dong Wang, Nianzeng Xing, Zejun Xiao, Yajian Li. Diagnostic value of ⁶⁸Ga-PSMA-PET /CT in pelvic lymph node metastasis of prostate cancer [J]. Chinese Journal of Endourology(Electronic Edition), 2023, 17(03): 214-218.
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[11]	Xiaofeng Zhang, Jun Wang. Analysis of ultrasonic signs of inguinal hernia and femoral hernia and their differential diagnosis value [J]. Chinese Journal of Hernia and Abdominal Wall Surgery(Electronic Edition), 2023, 17(05): 615-618.
[12]	Fengshang Zhu, Ling She, Yongnian Ding, Changqing Yang. Maintaining vigilance in the differential diagnosis of inflammatory bowel disease and rare bowel disorders [J]. Chinese Journal of Digestion and Medical Imageology(Electronic Edition), 2023, 13(05): 273-276.
[13]	Feng Wu, Xiaolu Liu, Qian Wang, Juan Xu. Diagnostic value of color Doppler ultrasound for gastric stromal tumor [J]. Chinese Journal of Digestion and Medical Imageology(Electronic Edition), 2023, 13(04): 229-231.
[14]	Sugui Wang, Liyuan Huang, Fujin Jiang, Ziyu Wu, Xianyun Zhang, Qiang Li, Dali Yan. Role of HNRNPA2B1 in prostate cancer and screening of HNRNPA2B1-targeted active components of traditional Chinese medicine [J]. Chinese Journal of Clinicians(Electronic Edition), 2023, 17(06): 731-736.
[15]	Xiaoqing Zhou, Bo Ning, Enqiang Linghu. Research progress in diagnosis and treatment of mesenteric panniculitis [J]. Chinese Journal of Gastrointestinal Endoscopy(Electronic Edition), 2023, 10(04): 267-270.

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