Therapeutic evaluation of the 1 470 nm laser enucleation for benign prostatic hyperplasia

doi:10.3877/cma.j.issn.1674-3253.2025.02.009

Abstract

Abstract:

Objective

To evaluate effectiveness of the 1 470nm laser enucleation in the management of benign prostatic hyperplasia.

Methods

The clinical data of 46 patients with BPH who underwent 1 470 nm laser enucleation and 40 patients who underwent TURP in the First Hospital of China Medical University from January 2019 to June 2022 were retrospectively analyzed.Age，level of PSA，volume of the prostate，IPSS，QOL，RUV，Q_max，operative time，blood loss，sodium loss of blood，time of bladder irrigation，time of indwelling catheter，in-hospital time and complications were collected.The age，level of PSA，volume of the prostate，IPSS，QOL，RUV，Q_max between the two groups showed no significant difference before operation （P＞0.05）.

Results

All patients received operation successfully.Postoperative follow-up was conducted for 6-30 months.The 1 470 nm group showed advantages in operative time，blood loss volume，the sodium loss of blood，the time of bladder irrigation，the time of indwelling catheter，inhospital time and IPSS after 6 months follow-up （P＜0.05），but the QOL and RUV 6 months after operation showed no difference （P＞0.05）.

Conclusions

1 470 nm enucleation of the prostate is safe，effective，and minimal invasive for the management of benign prostatic hyperplasia.

Key words: 1 470 nm laser, Enucleation of the prostate, Benign prostatic hyperplasia

Di Kan, Hao Zhang. Therapeutic evaluation of the 1 470 nm laser enucleation for benign prostatic hyperplasia[J]. Chinese Journal of Endourology(Electronic Edition), 2025, 19(02): 181-186.

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Figures/Tables 3

组别	例数	年龄［岁，（ $\overset{ˉ}{x}$ ±s ）］	tPSA［ng/ml，（ $\overset{ˉ}{x}$ ±s ）］	前列腺体积［ml，（ $\overset{ˉ}{x}$ ±s ）］	IPSS［分，（ $\overset{ˉ}{x}$ ±s ）］	RUV［ml，（ $\overset{ˉ}{x}$ ±s ）］	Q_max［ml/s，（ $\overset{ˉ}{x}$ ±s ）］	QOL［分，（ $\overset{ˉ}{x}$ ±s ）］	术前尿细菌培养阳性（例）	合并膀胱结石（例）
1 470 nm剜除组	46	72.5±6.6	2.3±0.8	71±18	26±4	90±35	9.3±2.7	4.4±0.9	11	5
TURP组	40	72.6±7.2	2.4±0.8	72±18	25±4	99±42	9.3±2.3	4.4±1.0	8	3
统计值		t=0.071	t=0.592	t=0.219	t=0.957	t=1.073	t＜0.001	t＜0.001	χ ²=0.190	-
P值		0.944	0.555	0.781	0.341	0.286	＞0.999	＞0.999	0.288	0.721

组别	例数	年龄［岁，（ $\overset{ˉ}{x}$ ±s ）］	tPSA［ng/ml，（ $\overset{ˉ}{x}$ ±s ）］	前列腺体积［ml，（ $\overset{ˉ}{x}$ ±s ）］	IPSS［分，（ $\overset{ˉ}{x}$ ±s ）］	RUV［ml，（ $\overset{ˉ}{x}$ ±s ）］	Q_max［ml/s，（ $\overset{ˉ}{x}$ ±s ）］	QOL［分，（ $\overset{ˉ}{x}$ ±s ）］	术前尿细菌培养阳性（例）	合并膀胱结石（例）
1 470 nm剜除组	46	72.5±6.6	2.3±0.8	71±18	26±4	90±35	9.3±2.7	4.4±0.9	11	5
TURP组	40	72.6±7.2	2.4±0.8	72±18	25±4	99±42	9.3±2.3	4.4±1.0	8	3
统计值		t=0.071	t=0.592	t=0.219	t=0.957	t=1.073	t＜0.001	t＜0.001	χ ²=0.190	-
P值		0.944	0.555	0.781	0.341	0.286	＞0.999	＞0.999	0.288	0.721

组别	例数	手术时间（min）	血红蛋白降低（g/L）	血钠稀释（mmol/L）	持续膀胱冲洗时间（h）	留置尿管时间（d）	住院天数（d）	术后6个月IPSS（分）	术后6个月QOL（分）	术后6个月RUV（ml）
1 470 nm剜除组	46	77±11	11±5	6.0±1.5	39±10	6.5±0.9	10.1±1.5	3.7±2.6	1.0±0.9	11±7
TURP组	40	83±12	14±6	8.0±2.1	48±10	8.1±2.1	10.9±1.6	2.4±2.2	0.8±0.6	10±6
t值		2.732	2.355	5.211	3.966	4.587	2.483	2.525	1.225	0.694
P值		0.008	0.021	＜0.001	＜0.001	＜0.001	0.015	0.013	0.224	0.489

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