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中华腔镜泌尿外科杂志(电子版) ›› 2023, Vol. 17 ›› Issue (06) : 553 -557. doi: 10.3877/cma.j.issn.1674-3253.2023.06.002

临床研究

基于MUSE-DWI与SS-DWI技术在前列腺癌图像中的对比研究
李全喜, 唐辉军, 张健生, 杨飞()   
  1. 510630 广州,中山大学附属第三医院放射科
    510630 广州,中山大学附属第三医院泌尿外科
  • 收稿日期:2023-09-11 出版日期:2023-12-01
  • 通信作者: 杨飞
  • 基金资助:
    广东省医学科学技术研究基金项目(A2019560)

Comparative study of multiplexed sensitivity-encoding diffusion weighted imaging and single-shot echo-planar diffusion weighted imaging in prostate cancer images

Quanxi Li, Huijun Tang, Jiansheng Zhang, Fei Yang()   

  1. Department of Radiology, the Third Affiliated Hospital of Sun Yat-sen University, Guangzhou 510630, China
    Department of Urology, the Third Affiliated Hospital of Sun Yat-sen University, Guangzhou 510630, China
  • Received:2023-09-11 Published:2023-12-01
  • Corresponding author: Fei Yang
引用本文:

李全喜, 唐辉军, 张健生, 杨飞. 基于MUSE-DWI与SS-DWI技术在前列腺癌图像中的对比研究[J]. 中华腔镜泌尿外科杂志(电子版), 2023, 17(06): 553-557.

Quanxi Li, Huijun Tang, Jiansheng Zhang, Fei Yang. Comparative study of multiplexed sensitivity-encoding diffusion weighted imaging and single-shot echo-planar diffusion weighted imaging in prostate cancer images[J]. Chinese Journal of Endourology(Electronic Edition), 2023, 17(06): 553-557.

目的

研究基于复合灵敏编码-弥散加权成像(MUSE-DWI)与单次激发平面回波-弥散加权成像(SS-DWI)在前列腺癌(PCa)图像的定量评估及主观分析。

方法

以中山大学附属第三医院经病理证实的146例PCa患者的MUSE-DWI及SS-DWI图像为研究对象,回顾性定量分析两种序列图像的信噪比(SNR)、对比度-信噪比(CNR)、表观扩散系数(ADC)及主观评价。

结果

MUSE-DWI检测PCa的图像较SS-DWI更清晰。MUSE-DWI的SNR及CNR明显高于SS-DWI图像(38±13) vs(18±7),(43±24)vs(18±7),差异均具有统计学意义(P<0.001);MUSE-DWI与SS-DWI的ADC值分别为[(0.75±0.14)vs(0.74±0.13),P=0.020]。两名医师主观评分一致性高,Kappa值分别为0.764(MUSE-DWI)和0.691(SS-DWI)。MUSE-DWI图像总评分(229.0±5.7)高于SS-DWI(127.0±5.2);MUSE-DWI图像评分高于SS-DWI [(3.7±3.4)vs(2.1±1.0),P<0.05]。

结论

对比SS-DWI,MUSE-DWI检测PCa的图像更清晰,SNR、CNR更高,且医师主观评分更高,辅助临床对PCa的诊疗更有价值。

Objective

To investigate the quantitative evaluation and subjective analysis of multiplexed sensitivity-encoding diffusion weighted imaging (MUSE-DWI) versus single-shot echo-planar diffusion weighted imaging (SS-DWI) in prostate cancer (PCa).

Methods

MUSE-DWI and SS-DWI images of 146 pathologically confirmed PCa patients in the Third Affiliated Hospital of Sun Yat-sen University was performed to quantify the signal to noise ratio (SNR), contrast signal to noise ratio (CNR), apparent diffusion coefficient (ADC) and subjective evaluation of the two sequences were quantitatively analyzed retrospectively.

Results

The SNR and CNR of MUSE-DWI were significantly higher than those of SS-DWI (38±13) vs (18±7), (43±24) vs (18±7), the differences were statistically significant (P<0.001); the ADC values of MUSE-DWI and SS-DWI were (0.75 ±0.14) vs (0.74±0.13), respectively, P=0.020. The subjective scores were in high agreement between the two physicians, with kappa values of 0.764 (MUSE-DWI) and 0.691 (SS-DWI), respectively. Total MUSE-DWI image scores (229.0±5.7) were higher than SS-DWI (127.0±5.2); MUSE-DWI image scores were higher than SS-DWI [(3.7±3.4) vs (2.1±1.0), P<0.05].

Conclusions

Compared with SS-DWI, MUSE-DWI has clearer images, higher SNR and CNR for detecting PCa, and higher subjective physician scores, which are valuable to assist clinical diagnosis and treatment of PCa.

表1 146例患者MUSE-DWI与SS-DWI序列前列腺癌图像质量的比较(±s
表2 两名医师对146例前列腺癌患者SS-DWI和MUSE-DWI图像质量评分及一致性检验(±s
图1 一例75岁前列癌患者不同序列MRI图像对比注:a为T2WI,b为单次激发平面回波-弥散加权成像(SS-DWI)与复合灵敏编码-弥散加权成像(MUSE-DWI),c为表观弥散系数ADC图,d为增强图。弥散b值(1 500 s/mm2)对比两组(MUSE-DWI和SS-DWI),MUSE序列整体病灶凸显更明显,伪影更低,细节分辨率更高,边缘和边界更清晰
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