Abstract:

In recent years，due to environmental pollution，dietary changes and other factors，the incidence rate of prostate cancer （PCa） has gradually increased，affecting male's health and life expectancy.Early and accurate diagnosis and treatment are keys to prolonging the survival time of patients.Previously，prostate-specific antigen （PSA） was used for the diagnosis of prostate cancer （PCa），but it was prone to misdiagnosis due to factors such as age and inflammation，necessitating biopsy.However，biopsy is invasive，so new biomarkers are urgently needed to improve the clinical diagnosis of PCa and guide treatment decisions.Exosomes belong to a subclass of extracellular vesicles and can serve as carriers for intercellular information transmission.Previous studies have shown that exosomes contain various proteins and RNAs that are crucial for the progression of PCa，and have potential in PCa diagnosis.This article reviews the biological characteristics of exosomes，their role in the development of PCa，and elaborates on their potential applications in the diagnosis and treatment of PCa.

Key words: Exosome, Body fluids, Prostate cancer, Tumor microenvironment (TME)